Department of Psychology.
Department of Health Studies, University of Chicago.
J Abnorm Psychol. 2013 Nov;122(4):1142-53. doi: 10.1037/a0034151.
Previous research using confirmatory factor analysis to model psychopathology comorbidity has supported the hypothesis of a broad general factor (i.e., a "bifactor"; Holzinger & Swineford, 1937) of psychopathology in children, adolescents, and adults, with more specific higher order internalizing and externalizing factors reflecting additional shared variance in symptoms (Lahey et al., 2012; Lahey, van Hulle, Singh, Waldman, & Rathouz, 2011). The psychological nature of this general factor has not been explored, however. The current study tested a prediction, derived from the spectrum hypothesis of personality and psychopathology, that variance in a general psychopathology bifactor overlaps substantially-at both phenotypic and genetic levels-with the dispositional trait of negative emotionality. Data on psychopathology symptoms and dispositional traits were collected from both parents and youth in a representative sample of 1,569 twin pairs (ages 9-17 years) from Tennessee. Predictions based on the spectrum hypothesis were supported, with variance in negative emotionality and the general factor overlapping substantially at both phenotypic and etiologic levels. Furthermore, stronger correlations were found between negative emotionality and the general psychopathology factor than among other dispositions and other psychopathology factors.
先前使用验证性因素分析来构建精神病理学共病模型的研究支持了儿童、青少年和成人精神病理学的广义因素（即“双因素”；Holzinger & Swineford，1937）假说，更具体的高阶内在和外在因素反映了症状的额外共享方差（Lahey 等人，2012；Lahey、van Hulle、Singh、Waldman 和 Rathouz，2011）。然而，这种广义因素的心理性质尚未得到探索。本研究检验了一个预测，该预测源自人格和精神病理学的谱系假说，即广义精神病理学双因素的方差在表型和遗传水平上与负性情绪的特质性倾向有很大的重叠。来自田纳西州的 1569 对双胞胎（9-17 岁）的代表性样本中，从父母和青少年那里收集了精神病理学症状和特质性倾向的数据。基于谱系假说的预测得到了支持，负性情绪和广义因素的方差在表型和病因水平上都有很大的重叠。此外，负性情绪与一般精神病理学因素之间的相关性比其他特质和其他精神病理学因素之间的相关性更强。
