Division of Cardiac Surgery, Department of Cardiac and Thoracic Surgery, University Hospital Münster, Münster, Germany.
Curr Opin Anaesthesiol. 2014 Feb;27(1):65-71. doi: 10.1097/ACO.0000000000000038.
Meanwhile mitral valve insufficiency is probably the second most common heart valve disease represented in cardiac surgery. Due to low perioperative morbidity and mortality, nowadays mitral valve repair can even be considered in asymptomatic patients. The enhancements of minimally invasive surgical techniques led to a decrease in surgical trauma and accelerated postoperative recovery, resulting in increased acceptance of these operating techniques. Therefore, the present review focuses on the different surgical access ways to the mitral valve and their significance for mitral valve repair.
The emergence of transcatheter approaches to mitral valve repair has focused attention on outcomes after surgical mitral valve repair. Results from the EVEREST II trial demonstrated worse short-term major adverse event rates for surgical repair. Recently, several studies were published analyzing contemporary outcomes, morbidity, mortality, and quality of life after conventional and minimally invasive surgical mitral valve repair to establish benchmarks for future therapeutic comparisons.
Today mitral valve repair is the gold standard for treatment of significant mitral valve regurgitation with low perioperative morbidity and mortality and excellent long-term results. It can be performed through minimally invasive surgical techniques without compromising long-term durability of repair results, but with a decrease in surgical trauma and accelerated postoperative recovery. Currently, endovascular therapy for mitral regurgitation (e.g., the MitraClip procedure) should be limited to patients who otherwise would not be eligible for surgery.
同时,二尖瓣关闭不全可能是心脏外科中第二常见的心脏瓣膜病。由于围手术期发病率和死亡率低,如今,二尖瓣修复术甚至可以考虑用于无症状患者。微创外科技术的进步降低了手术创伤,加速了术后恢复,从而提高了对这些手术技术的接受程度。因此,本综述重点关注二尖瓣的不同手术入路及其对二尖瓣修复的意义。
经导管二尖瓣修复术的出现使人们对二尖瓣修复术后的结果更加关注。 EVEREST II 试验的结果表明,手术修复的短期主要不良事件发生率更高。最近,有几项研究发表,分析了传统和微创二尖瓣修复术的当代结果、发病率、死亡率和生活质量,为未来的治疗比较建立了基准。
如今,二尖瓣修复术是治疗严重二尖瓣反流的金标准,其围手术期发病率和死亡率低,长期效果极佳。它可以通过微创外科技术进行,而不会影响修复效果的长期耐久性,但会降低手术创伤并加速术后恢复。目前,二尖瓣反流的经导管治疗(例如,MitraClip 手术)应仅限于不符合手术条件的患者。