Department of Chemistry, University of Michigan , 930 North University Avenue, Ann Arbor, Michigan 48109, United States.
J Am Chem Soc. 2014 Jan 29;136(4):1218-21. doi: 10.1021/ja4113462. Epub 2014 Jan 15.
The development of a room-temperature lignin degradation strategy consisting of a chemoselective benzylic oxidation with a recyclable oxidant ([4-AcNH-TEMPO]BF4) and a catalytic reductive C-O bond cleavage utilizing the photocatalyst [Ir(ppy)2(dtbbpy)]PF6 is described. This system was tested on relevant lignin model substrates containing β-O-4 linkages to generate fragmentation products in good to excellent yields.
本文描述了一种室温下木质素降解策略的发展，该策略包括使用可回收氧化剂（[4-AcNH-TEMPO]BF4）进行选择性苄基氧化，以及利用光催化剂 [Ir(ppy)2(dtbbpy)]PF6 进行催化还原 C-O 键断裂。该体系在含有β-O-4 键的相关木质素模型底物上进行了测试，以优异的收率生成了碎片化产物。
