Bressan Eriberto, Tessarolo Francesco, Sbricoli Luca, Caola Iole, Nollo Giandomenico, Di Fiore Adolfo
*Chairman, Department of Neurosciences, Institute of Clinical Dentistry, University of Padova, Padova, Italy. †Resident, Healthcare Research and Innovation Program (IRCS), Bruno Kessler Foundation, Trento, Italy; Department of Industrial Engineering, University of Trento, Trento, Italy. ‡Resident, Department of Neurosciences, Institute of Clinical Dentistry, University of Padova, Padova, Italy. §Resident, Department of Medicine Laboratory, APSS, Trento, Italy.
Implant Dent. 2014 Feb;23(1):64-8. doi: 10.1097/ID.0000000000000018.
The study aimed at evaluating the effect of chlorhexidine (CHX) in preventing plaque biofilm (PB) formation on healing abutments (HAs) in patients rehabilitated with osseointegrated implants.
Fifty HAs were placed in 34 voluntary patients 1 week after implant surgery (test group). After 7 days, a new set of 50 HAs was placed in the same implant sites and removed 1 week after (control group). During the 2 testing periods, patients were instructed to apply: CHX mouth rinsing twice daily and no brushing (test); no CHX mouth rinsing and no brushing (control). Scanning electron microscopy and image analysis were blindly used to objectively quantify PB amount on removed HAs.
Median values and interquartile ranges of the percent ratio of titanium surface covered from PB were 0.9 (0.1-4.1) and 1.2 (0.1-11.6) for test and control groups, respectively (P = 0.0275).
CHX mouth rinsing significantly limited plaque formation on HAs, being a valid contribution to mechanical brushing in early phases of plaque control on dental implants.
本研究旨在评估洗必泰（CHX）对接受骨整合种植体修复患者的愈合基台（HA）上菌斑生物膜（PB）形成的预防作用。
在种植手术后1周，将50个愈合基台放置于34名志愿患者体内（试验组）。7天后，在相同种植部位放置新的一组50个愈合基台，并于1周后取出（对照组）。在两个测试阶段，指导患者进行如下操作：试验组每天使用洗必泰漱口水两次且不刷牙；对照组不使用洗必泰漱口水且不刷牙。采用扫描电子显微镜和图像分析技术，在不了解分组情况的条件下客观量化取出的愈合基台上的菌斑量。
试验组和对照组中，被菌斑覆盖的钛表面百分比的中位数及四分位间距分别为0.9（0.1 - 4.1）和1.2（0.1 - 11.6）（P = 0.0275）。
使用洗必泰漱口水可显著减少愈合基台上的菌斑形成，这对牙种植体菌斑控制早期的机械刷牙起到了有效的辅助作用。
