1 Department of Radiology, Imaging Research Center, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5033, Cincinnati, OH 45229-3039.
AJR Am J Roentgenol. 2014 Jan;202(1):W95-W105. doi: 10.2214/AJR.13.10613.
The objective of our study was to develop a small 1.5-T MRI system for neonatal imaging that can be installed in the neonatal ICU (NICU) and to evaluate its performance in 15 neonates.
A 1.5-T MR system designed for orthopedic use was adapted for neonatal imaging. Modifications included raising and leveling the magnet, construction of a patient table, and integration of imaging electronics from a high-performance adult-sized scanner. The system was used to perform MR examinations of the brain, abdomen, and chest in 15 medically stable neonates using standard clinical protocols. The scanning time was limited to 60 minutes. The MR examinations were performed without administering sedation to the patients. ECG, heart rate, oxygen saturation, and temperature were monitored continuously throughout the examination. The images were evaluated by two pediatric radiologists for overall study quality, motion artifact, spatial resolution, signal-to-noise ratio, and contrast.
All 15 neonates were successfully imaged without sedation. No adverse MRI-related events were noted. In total, 19 brain and seven abdominal examinations were performed. Six chest and two cardiac examinations were also obtained. Gross (versus physiologic) subject motion proved to be the most influential factor in determining overall study and image quality. High-quality diagnostic images were obtained at each anatomic location.
The customized neonatal MRI system provides state-of-the-art MRI capabilities in the NICU.
本研究旨在开发一款适用于新生儿成像的小型 1.5T MRI 系统，该系统可安装在新生儿重症监护病房（NICU）中，并对 15 名新生儿的性能进行评估。
我们设计了一款适用于骨科的 1.5T MR 系统，并对其进行了改造，以适应新生儿成像。改造包括抬高和调平磁体、构建患者台以及整合高性能成人型扫描仪的成像电子设备。该系统用于使用标准临床方案对 15 名医学上稳定的新生儿进行脑、腹部和胸部的 MR 检查。扫描时间限制在 60 分钟内。在对患者进行镇静的情况下进行了 MR 检查。在整个检查过程中，连续监测心电图、心率、血氧饱和度和体温。两名儿科放射科医生对整体研究质量、运动伪影、空间分辨率、信噪比和对比度进行了评估。
所有 15 名新生儿均在未镇静的情况下成功成像。未观察到与 MRI 相关的不良事件。共进行了 19 次脑部和 7 次腹部检查。还获得了 6 次胸部和 2 次心脏检查。总体而言（与生理相关），受检者运动被证明是决定整体研究和图像质量的最主要因素。在每个解剖部位都获得了高质量的诊断图像。
定制的新生儿 MRI 系统为新生儿重症监护病房提供了最先进的 MRI 功能。
