Papakostas John C, Avgos Stavros, Arnaoutoglou Eleni, Nassis Christos, Peroulis Michalis, Bali Christina, Papadopoulos George, Matsagkas Miltiadis I
Department of Surgery-Vascular Surgery Unit, Medical School, University of Ioannina, Ioannina, Greece.
Department of Anesthesiology, Medical School, University of Ioannina, Ioannina, Greece.
Ann Vasc Surg. 2014 Jul;28(5):1213-8. doi: 10.1016/j.avsg.2013.10.021. Epub 2013 Dec 24.
To report the early and long-term results of Vascu-Guard bovine pericardium (BP) for patch angioplasty in carotid endarterectomy (CEA).
We retrospectively analyzed the data of 256 CEAs with BP patch closure performed in 238 patients during the past 12 years in our department. Patch-related complications (restenosis, infection, and aneurysm formation) and early and late (12 to 144 months follow-up) clinical outcomes were recorded and statistically analyzed.
Thirty-day postoperative stroke rate was 1.2% (3/256) with zero mortality. Major complications occurred in 3.5% (9 of 256) of the procedures and cranial nerve injury in 4.3% (11 of 256). At 12 years, cumulative estimates of freedom from any stroke, stroke-free survival, and freedom from restenosis were 88.4% (standard error [SE]: 3.3%), 60% (SE: 7.8%), and 98.3% (SE: 0.8%), respectively. No patient experienced patch infection or aneurysm formation.
This series shows the efficacy, safety, and durability of CEA with BP patch closure, in both the short and long term. BP combines the advantages of vein and synthetic patches, representing a suitable option when performing CEA.
报告Vascu-Guard牛心包（BP）用于颈动脉内膜切除术（CEA）中补片血管成形术的早期和长期结果。
我们回顾性分析了过去12年中在我科238例患者中进行的256例采用BP补片闭合的CEA的数据。记录并统计分析补片相关并发症（再狭窄、感染和动脉瘤形成）以及早期和晚期（随访12至144个月）的临床结果。
术后30天的卒中率为1.2%（3/256），死亡率为零。3.5%（256例中的9例）的手术发生了主要并发症，4.3%（256例中的11例）发生了脑神经损伤。在12年时，无任何卒中、无卒中生存和无再狭窄的累积估计分别为88.4%（标准误差[SE]：3.3%）、60%（SE：7.8%）和98.3%（SE：0.8%）。没有患者发生补片感染或动脉瘤形成。
本系列研究显示了CEA采用BP补片闭合在短期和长期的有效性、安全性和耐用性。BP兼具静脉补片和合成补片的优点，是进行CEA时的合适选择。
