酶免疫分析法快速检测空肠弯曲菌抗原可提高阳性率。
Rapid detection of Campylobacter antigen by enzyme immunoassay leads to increased positivity rates.
机构信息
David Geffen School of Medicine, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, California, USA.
出版信息
J Clin Microbiol. 2013 Feb;51(2):618-20. doi: 10.1128/JCM.02565-12. Epub 2012 Nov 21.
Abstract
Campylobacter antigen detection by enzyme immunoassay (EIA) provides rapid results compared to traditional culture. However, concern exists regarding specificity. Verification studies of an EIA compared to culture revealed a positive predictive value (PPV) of 91%, whereas PPV fell to 42% during routine diagnostic testing. We suggest all positive EIA results be confirmed via culture.
摘要
与传统培养相比，酶免疫分析（EIA）检测弯曲菌抗原可快速获得结果。然而，其特异性令人担忧。EIA 与培养的验证研究显示阳性预测值（PPV）为 91%，而在常规诊断检测中 PPV 降至 42%。我们建议所有阳性 EIA 结果均通过培养确认。
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