Department of Chemistry, Fuzhou University , Fuzhou 350108, China.
Org Lett. 2014 Jan 17;16(2):524-7. doi: 10.1021/ol403406y. Epub 2013 Dec 27.
A catalytic trifluoromethylselenolation of aryl and alkyl halides by a Cu(I) catalyst has been developed. A key intermediate, [(phen)Cu(SeCF3)]2 (5) was successfully isolated and characterized by X-ray diffraction. The important role of silver in the transmetalation process during the catalytic cycle was elucidated. A wide range of trifluoromethylselanes have been prepared from readily available starting materials from a method that tolerates various important functional groups.
一种由 Cu(I) 催化剂催化的芳基和烷基卤化物的三氟甲基硒化反应已经被开发出来。一个关键的中间体，[(phen)Cu(SeCF3)]2（5），通过 X 射线衍射成功地被分离和表征。在催化循环中，银在转金属过程中的重要作用也被阐明了。通过一种方法，可以从易得的起始原料中制备出多种三氟甲基硒烷，该方法容忍各种重要的官能团。
