Fonseca Wald Eric L A, van den Borst Bram, Gosker Harry R, Schols Annemie M W J
Department of Respiratory Medicine, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University Medical Center+, Maastricht, the Netherlands.
Respirology. 2014 Feb;19(2):176-184. doi: 10.1111/resp.12229. Epub 2013 Dec 24.
Dietary intake attracts increasing interest in the risk for and progression of chronic obstructive pulmonary disease (COPD). In particular, dietary fibre and fatty acids have drawn specific attention for their immunomodulating potential. The study aimed to review the current evidence on the potential roles of dietary fibre or fatty acid intake in the risk and progression of COPD. Pubmed, EMBASE, Cochrane Collaboration Database and conference databases for original studies in adults addressing the association between fibre or fatty acid intake and COPD in terms of risk, lung function and respiratory symptoms were searched. Nine articles were included of which four reported on dietary fibre and five on fatty acids. Data of studies could not be pooled because of methodological diversity. Greater intake of dietary fibre has been consistently associated with reduced COPD risk, better lung function and reduced respiratory symptoms. Results on the associations between fatty acids and COPD are inconsistent. Dietary quality deserves further attention in developing COPD prevention and management programs.
饮食摄入在慢性阻塞性肺疾病（COPD）的风险及病情进展方面引发了越来越多的关注。特别是膳食纤维和脂肪酸因其免疫调节潜力而受到了特别关注。本研究旨在综述当前关于膳食纤维或脂肪酸摄入在COPD风险及病情进展中潜在作用的证据。检索了Pubmed、EMBASE、Cochrane协作数据库以及会议数据库，以查找针对成年人中膳食纤维或脂肪酸摄入与COPD在风险、肺功能及呼吸道症状方面关联的原始研究。纳入了9篇文章，其中4篇报道了膳食纤维，5篇报道了脂肪酸。由于方法学的多样性，研究数据无法合并。膳食纤维摄入量增加一直与COPD风险降低、肺功能改善及呼吸道症状减轻相关。脂肪酸与COPD之间关联的结果并不一致。在制定COPD预防和管理方案时，饮食质量值得进一步关注。
