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体育活动与脊椎治疗结果研究(SPORT)中腰椎管狭窄症患者物理治疗与长期预后的关联。

Associations between physical therapy and long-term outcomes for individuals with lumbar spinal stenosis in the SPORT study.

作者信息

Fritz Julie M, Lurie Jon D, Zhao Wenyan, Whitman Julie M, Delitto Anthony, Brennan Gerard P, Weinstein James N

机构信息

Department of Physical Therapy, University of Utah, 520 Wakara Way, Salt Lake City, UT 84108, USA; Physical Therapy Division, Intermountain Healthcare, 5848 South 300 East Murray, Salt Lake City, UT 84107, USA.

Department of Medicine, Dartmouth Medical School, 1 Rope Ferry Rd, Hanover, NH 03755, USA; The Dartmouth Institute for Health Policy and Clinical Practice, Dartmouth College, 35 Centerra Pkwy, Lebanon, NH 03766, USA.

出版信息

Spine J. 2014 Aug 1;14(8):1611-21. doi: 10.1016/j.spinee.2013.09.044. Epub 2013 Oct 23.

Abstract

BACKGROUND CONTEXT

A period of nonsurgical management is advocated before surgical treatment for most patients with lumbar spinal stenosis. Currently, little evidence is available to define optimal nonsurgical management. Physical therapy is often used, however its use and effectiveness relative to other nonsurgical strategies has not been adequately explored.

PURPOSE

Describe the use of physical therapy and other nonsurgical interventions by patients with lumbar spinal stenosis and examine the relationship between physical therapy and long-term prognosis.

STUDY DESIGN

Secondary analysis of the Spine Patient Outcomes Research Trial (SPORT) combining data from randomized and observational studies.

SETTING

Thirteen spine clinics in 11 states in the United States.

PATIENT SAMPLE

Patients with lumbar spinal stenosis receiving nonsurgical management including those who did or did not receive physical therapy within 6 weeks of enrollment.

OUTCOME MEASURES

Primary outcome measures included crossover to surgery, the bodily pain and physical function scales changes from the Survey Short Form 36 (SF-36), and the modified Oswestry Disability Index. Secondary outcome measures were patient satisfaction and the Sciatica Bothersomeness Index.

METHODS

Baseline characteristics and rates of crossover to surgery were compared between patients who did or did not receive physical therapy. Baseline factors predictive of receiving physical therapy were examined with logistic regression. Mixed effects models were used to compare outcomes between groups at 3 and 6 months and 1 year after enrollment adjusted for baseline severity and patient characteristics.

RESULTS

Physical therapy was used in the first 6 weeks by 90 of 244 patients (37%) and was predicted by the absence of radiating pain and being single instead of married. Physical therapy was associated with a reduced likelihood of crossover to surgery after 1 year (21% vs. 33%, p=.045), and greater reductions on the Short Form 36 physical functioning scale after 6 months (mean difference=6.0, 95% confidence interval: 0.2-11.7) and 1 year (mean difference=6.5, 95% confidence interval: 0.6-12.4). There were no differences in bodily pain or Oswestry scores across time.

CONCLUSIONS

Many patients with lumbar spinal stenosis pursuing conservative management receive physical therapy. Using physical therapy was associated with reduced likelihood of patients receiving surgery within 1 year. Results for other outcomes were mixed with no differences in several measures. Further research is needed to examine the effectiveness of physical therapy relative to other nonsurgical management strategies for patients with lumbar spinal stenosis.

摘要

背景信息

对于大多数腰椎管狭窄症患者,提倡在手术治疗前进行一段时间的非手术治疗。目前,几乎没有证据可用于确定最佳的非手术治疗方案。物理治疗经常被使用,然而其相对于其他非手术策略的使用情况和有效性尚未得到充分研究。

目的

描述腰椎管狭窄症患者对物理治疗和其他非手术干预措施的使用情况,并研究物理治疗与长期预后之间的关系。

研究设计

对脊柱患者预后研究试验(SPORT)进行二次分析,该试验结合了随机研究和观察性研究的数据。

研究地点

美国11个州的13家脊柱诊所。

患者样本

接受非手术治疗的腰椎管狭窄症患者,包括在入组后6周内接受或未接受物理治疗的患者。

观察指标

主要观察指标包括转为手术治疗、36项简明健康状况调查量表(SF-36)中身体疼痛和身体功能量表的变化,以及改良的奥斯维斯特残疾指数。次要观察指标为患者满意度和坐骨神经痛困扰指数。

方法

比较接受或未接受物理治疗的患者的基线特征和转为手术治疗的比例。采用逻辑回归分析预测接受物理治疗的基线因素。使用混合效应模型比较入组后3个月、6个月和1年时两组之间的结局,对基线严重程度和患者特征进行校正。

结果

244例患者中有90例(37%)在最初6周内接受了物理治疗,预测因素为无放射性疼痛以及单身而非已婚。物理治疗与1年后转为手术治疗的可能性降低相关(21%对33%,p = 0.045),并且在6个月(平均差异=6.0,95%置信区间:0.2 - 11.7)和1年(平均差异=6.5,95%置信区间:0.6 - 12.4)后,36项简明健康状况调查量表身体功能量表的改善幅度更大。不同时间点的身体疼痛或奥斯维斯特评分没有差异。

结论

许多寻求保守治疗的腰椎管狭窄症患者接受了物理治疗。使用物理治疗与患者在1年内接受手术的可能性降低相关。其他结局的结果不一,在多项指标上没有差异。需要进一步研究以考察物理治疗相对于其他非手术治疗策略对腰椎管狭窄症患者的有效性。

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