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妊娠期输尿管镜治疗结石疾病的现状

Current status of ureteroscopy for stone disease in pregnancy.

作者信息

Ishii Hiro, Aboumarzouk Omar M, Somani Bhaskar K

机构信息

Department of Urology, University Hospital of Southampton NHS Foundation Trust, SO16 6YD, Southampton, UK.

出版信息

Urolithiasis. 2014 Feb;42(1):1-7. doi: 10.1007/s00240-013-0635-y. Epub 2013 Dec 29.

Abstract

Ureteroscopic management of urolithiasis in pregnancy has been on the rise. Technological advancements such as the development of the semi-rigid or flexible ureteroscope, improvements in the design of baskets used for retrieval and the availability of laser have enabled atraumatic fragmentation of stones. We did a systematic review of literature from January 1990 to December 2012. Data were analysed separately for the time period from January 1990 to June 2010 (Period 1) and for last 2.5 years from July 2010 to December 2012 (Period 2). Inclusion criteria were all English language articles with at least three patients reported. Data were extracted on the outcomes and complications reported in the literature. A total of 271 procedures (116 in period 1, 155 in period 2) across 21 studies were reported in the last 22 years. General anaesthesia was used in 38% (44/116) in period 1 and in 64% (99/155) in period 2. The average stone size (7.6 mm) and stone-free rate (SFR) (85%) were similar in both time periods. Fluoroscopy was used in 20% (23/116) and 24% (38/155) in period 1 and 2, respectively. There were fewer complications in period 1 (n = 9) than period 2 (n = 25). These complications were divided into obstetric (n = 5) and non-obstetric complications (n = 29). There were no maternal or foetal deaths during the 22 years. Stone treatment using ureteroscopic techniques in pregnancy can achieve a high success rate. Evidence suggests a rise in the risk of complications with increasing number of these procedures in pregnancy.

摘要

孕期输尿管镜治疗尿路结石的应用呈上升趋势。诸如半硬性或软性输尿管镜的发展、用于取石的网篮设计的改进以及激光的应用等技术进步,使得结石能够进行无创粉碎。我们对1990年1月至2012年12月的文献进行了系统回顾。分别分析了1990年1月至2010年6月(第1阶段)以及2010年7月至2012年12月的最后2.5年(第2阶段)的数据。纳入标准为所有至少报告了3例患者的英文文章。提取了文献中报道的结局和并发症数据。在过去22年中,21项研究共报告了271例手术(第1阶段116例,第2阶段155例)。第1阶段38%(44/116)的患者使用全身麻醉,第2阶段为64%(99/155)。两个时间段的平均结石大小(7.6毫米)和无石率(SFR)(85%)相似。第1阶段和第2阶段分别有20%(23/116)和24%(38/155)的患者使用了荧光镜检查。第1阶段的并发症(n = 9)少于第2阶段(n = 25)。这些并发症分为产科并发症(n = 5)和非产科并发症(n = 29)。在这22年中没有孕产妇或胎儿死亡。孕期使用输尿管镜技术治疗结石可获得较高的成功率。有证据表明,随着孕期此类手术数量的增加,并发症风险也在上升。

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