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Hippokratia. 2013 Apr;17(2):169-70.
2
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Fertilization and development of a blastocyst-stage embryo after selective intracytoplasmic sperm injection of a mature oocyte from a binovular zona pellucida: a case report.双卵透明带中成熟卵母细胞经卵胞浆内单精子注射后囊胚期胚胎的受精与发育：一例报告
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Binovular follicles in the adult human ovary.成年女性卵巢中的双卵卵泡。
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Biopsying, fragmentation and autotransplantation of fresh ovarian cortical tissue in infertile women with diminished ovarian reserve.对卵巢储备功能下降的不孕妇女进行新鲜卵巢皮质组织活检、分割和自体移植。
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本文引用的文献

1
Intracytoplasmic sperm injection allows fertilization and development of a chromosomally balanced embryo from a binovular zona pellucida.卵胞浆内单精子注射可使来自双卵透明带的染色体平衡胚胎实现受精并发育。
Hum Reprod. 1998 Sep;13(9):2575-8. doi: 10.1093/humrep/13.9.2575.
2
Fertilization and cleavage of oocytes from a binovular human ovarian follicle: a possible cause of dizygotic twinning and chimerism.来自双卵性人类卵巢卵泡的卵母细胞受精与分裂：双合子孪生和嵌合体的一个可能原因。
Fertil Steril. 1983 Dec;40(6):841-3. doi: 10.1016/s0015-0282(16)47490-x.
3
In vitro fertilization and cleavage of a single egg from a binovular follicle containing two individual eggs surrounded by a single zona pellucida.体外受精以及来自双卵卵泡的单个卵子的分裂，该双卵卵泡包含两个被单个透明带包围的独立卵子。
Fertil Steril. 1987 Apr;47(4):707-9. doi: 10.1016/s0015-0282(16)59128-6.
4
Binovular human ovarian follicles associated with in vitro fertilization: incidence and outcome.与体外受精相关的双卵性人类卵巢卵泡：发生率与结局
Fertil Steril. 1990 Nov;54(5):869-72. doi: 10.1016/s0015-0282(16)53948-x.

卵巢刺激后的双卵双胎复合体。四例报告。

Binovular complexes after ovarian stimulation. A report of four cases.

作者信息

Turkalj B, Kotanidis L, Nikolettos N

机构信息

Laboratory of Physiology & Laboratory of Reproductive Physiology-IVF.

IVF Unit, General University Hospital of Alexandroupolis, School of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.

出版信息

Hippokratia. 2013 Apr;17(2):169-70.

PMID:24376325
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3743624/
Abstract

BACKGROUND

Human ovary is known to contain polyovular follicles at birth but it is considered to be rare in adult ovaries.

CASES

Four cases are presented where binovular complexes were found after ovarian stimulation. The age of women was 22 to 33 years and all of them had a good response to ovarian stimulation. Two different types of binovular complexes were found. The mature oocytes of three binovular complexes were fertilized by ICSI. The generated embryos did not develop beyond the eight-cell stage.

CONCLUSION

The mature oocytes of binovular complexes can be fertilized but their developmental potential is limited.

摘要

背景

已知人类卵巢在出生时含有多卵卵泡，但在成年卵巢中被认为较为罕见。

病例

本文报告4例在卵巢刺激后发现双卵复合体的病例。患者年龄为22至33岁，均对卵巢刺激反应良好。发现了两种不同类型的双卵复合体。3个双卵复合体的成熟卵母细胞通过卵胞浆内单精子注射（ICSI）受精。所产生的胚胎未发育超过8细胞阶段。

结论

双卵复合体的成熟卵母细胞可以受精，但其发育潜力有限。