Leicht Gregor, Troschütz Stefan, Andreou Christina, Karamatskos Evangelos, Ertl Matthias, Naber Dieter, Mulert Christoph
Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Department of Psychiatry and Psychotherapy, Psychiatry Neuroimaging Branch (PNB), University Medical Center Hamburg-Eppendorf, Hamburg, Germany ; Department of Neurology, Ludwig-Maximilians-University, Munich, Germany ; Graduate school of systemic neuroscience, Ludwig-Maximilians-University, Munich, Germany.
PLoS One. 2013 Dec 20;8(12):e83414. doi: 10.1371/journal.pone.0083414. eCollection 2013.
The processing of reward and punishment stimuli in humans appears to involve brain oscillatory activity of several frequencies, probably each with a distinct function. The exact nature of associations of these electrophysiological measures with impulsive or risk-seeking personality traits is not completely clear. Thus, the aim of the present study was to investigate event-related oscillatory activity during reward processing across a wide spectrum of frequencies, and its associations with impulsivity and sensation seeking in healthy subjects.
During recording of a 32-channel EEG 22 healthy volunteers were characterized with the Barratt Impulsiveness and the Sensation Seeking Scale and performed a computerized two-choice gambling task comprising different feedback options with positive vs. negative valence (gain or loss) and high or low magnitude (5 vs. 25 points).
We observed greater increases of amplitudes of the feedback-related negativity and of activity in the theta, alpha and low-beta frequency range following loss feedback and, in contrast, greater increase of activity in the high-beta frequency range following gain feedback. Significant magnitude effects were observed for theta and delta oscillations, indicating greater amplitudes upon feedback concerning large stakes. The theta amplitude changes during loss were negatively correlated with motor impulsivity scores, whereas alpha and low-beta increase upon loss and high-beta increase upon gain were positively correlated with various dimensions of sensation seeking.
The findings suggest that the processing of feedback information involves several distinct processes, which are subserved by oscillations of different frequencies and are associated with different personality traits.
人类对奖惩刺激的处理似乎涉及多种频率的脑振荡活动，可能每种频率都有独特的功能。这些电生理测量与冲动或冒险人格特质之间关联的确切性质尚不完全清楚。因此，本研究的目的是调查健康受试者在奖励处理过程中广泛频率范围内的事件相关振荡活动，及其与冲动性和感觉寻求的关联。
在记录32通道脑电图期间，22名健康志愿者用巴拉特冲动性量表和感觉寻求量表进行了特征描述，并执行了一项计算机化的二选一赌博任务，该任务包括具有正性与负性效价（收益或损失）以及高或低量级（5分与25分）的不同反馈选项。
我们观察到，损失反馈后反馈相关负波的振幅以及θ波、α波和低β波频率范围内的活动增加更大，相反，收益反馈后高β波频率范围内的活动增加更大。在θ波和δ波振荡中观察到显著的量级效应，表明在涉及大赌注的反馈时振幅更大。损失期间的θ波振幅变化与运动冲动性得分呈负相关，而损失时α波和低β波增加以及收益时高β波增加与感觉寻求的各个维度呈正相关。
研究结果表明，反馈信息的处理涉及几个不同的过程，这些过程由不同频率的振荡支持，并与不同的人格特质相关。
