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针对热释光剂量测定法,评估Gafchromic EBT2薄膜用于测量高剂量率(192)铱近距离放射治疗源的各向异性函数。

Evaluation of Gafchromic EBT2 film for the measurement of anisotropy function for high-dose-rate (192)Ir brachytherapy source with respect to thermoluminescent dosimetry.

作者信息

Uniyal Satish C, Naithani Umesh C, Sharma Sunil D

机构信息

Department of Radiology, Himalayan Institute of Medical Sciences, Jolly Grant, Dehradun 248140, India.

Department of Physics, H N B Garhwal Central University, Campus Pauri, Pauri (Garhwal), Uttarakhand 246001, India.

出版信息

Rep Pract Oncol Radiother. 2010 Dec 7;16(1):14-20. doi: 10.1016/j.rpor.2010.11.003. eCollection 2010.

Abstract

AIM

The aim of this work was to assess the suitability of the use of a Gafchromic EBT2 film for the measurement of anisotropy function for microSelectron HDR (192)Ir (classic) source with a comparative dosimetry method using a Gafchromic EBT2 film and thermoluminescence dosimeters (TLDs).

BACKGROUND

Sealed linear radiation sources are commonly used for high dose rate (HDR) brachytherapy treatments. Due to self-absorption and oblique filtration of radiation in the source capsule material, an inherent anisotropy is present in the dose distribution around the source which can be described by a measurable two-dimensional anisotropy function, F(r, θ).

MATERIALS AND METHODS

Measurements were carried out in a specially designed and locally fabricated PMMA phantom with provisions to accommodate miniature LiF TLD rods and EBT2 film dosimeters at identical radial distances with respect to the (192)Ir source.

RESULTS

The data of anisotropy function generated by the use of the Gafchromic EBT2 film method are in agreement with their TLD measured values within 4%. The produced data are also consistent with their experimental and Monte Carlo calculated results for this source available in the literature.

CONCLUSION

Gafchromic EBT2 film was found to be a feasible dosimeter in determining anisotropy in the dose distribution of (192)Ir source. It offers high resolution and is a viable alternative to TLD dosimetry at discrete points. The method described in this paper is useful for comparing the performances of detectors and can be applied for other brachytherapy sources as well.

摘要

目的

本研究旨在通过使用Gafchromic EBT2薄膜和热释光剂量计(TLD)的比较剂量测定方法,评估Gafchromic EBT2薄膜用于测量microSelectron HDR(192)Ir(经典)源各向异性函数的适用性。

背景

密封线性放射源常用于高剂量率(HDR)近距离放射治疗。由于源包壳材料中辐射的自吸收和倾斜过滤,源周围剂量分布中存在固有的各向异性,可用可测量的二维各向异性函数F(r,θ)来描述。

材料与方法

在专门设计并本地制造的聚甲基丙烯酸甲酯(PMMA)体模中进行测量,该体模可在相对于(192)Ir源相同的径向距离处容纳微型氟化锂(LiF)TLD棒和EBT2薄膜剂量计。

结果

使用Gafchromic EBT2薄膜法生成的各向异性函数数据与TLD测量值的误差在4%以内。生成的数据也与文献中该源的实验和蒙特卡罗计算结果一致。

结论

发现Gafchromic EBT2薄膜是确定(192)Ir源剂量分布各向异性的可行剂量计。它具有高分辨率,是离散点处TLD剂量测定的可行替代方法。本文所述方法有助于比较探测器性能,也可应用于其他近距离放射治疗源。

相似文献

本文引用的文献

4
Dosimetric characteristics of 192Ir sources used in interstitial brachytherapy.
Appl Radiat Isot. 2001 Aug;55(2):189-95. doi: 10.1016/s0969-8043(00)00375-4.
7
Experimental determination of dosimetry functions of Ir-192 sources.
Med Phys. 1998 Dec;25(12):2279-87. doi: 10.1118/1.598457.

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