Reaction kinetic parameters for ion transport from steady-state current-voltage curves.
作者信息
Gradmann D, Klieber H G, Hansen U P
出版信息
Biophys J. 1987 Apr;51(4):569-85. doi: 10.1016/S0006-3495(87)83382-9.
Abstract
This study demonstrates possible ways to estimate the rate constants of reaction kinetic models for ion transport from steady-state current-voltage data as measured at various substrate concentrations. This issue is treated theoretically by algebraic reduction and extension of a reaction kinetic four-state model for uniport. Furthermore, an example for application is given; current-voltage data from an open K+ selective channel (Schroeder, J.I., R. Hedrich, and J.M. Fernandez, 1984, Nature (Lond.), 312:361-362) supplemented by some new data have been evaluated. The analysis yields absolute numerical estimates of the 14 rate constants of a six-state model, which is discussed in a wider context.
摘要
相似文献
1
Reaction kinetic parameters for ion transport from steady-state current-voltage curves.
Biophys J. 1987 Apr;51(4):569-85. doi: 10.1016/S0006-3495(87)83382-9.
2
Electrogenic ion transport by Na+,K+-ATPase.
Membr Cell Biol. 2000;13(6):745-88.
3
Gating current harmonics. II. Model simulations of axonal gating currents.
Biophys J. 1985 Sep;48(3):391-400. doi: 10.1016/S0006-3495(85)83795-4.
4
Thermodynamics and kinetics of electrogenic pumps.
Soc Gen Physiol Ser. 1984;38:17-32.
5
Open channel noise. VI. Analysis of amplitude histograms to determine rapid kinetic parameters.
Biophys J. 1991 Sep;60(3):577-87. doi: 10.1016/S0006-3495(91)82087-2.
6
A fully coupled transient excited state model for the sodium channel. I. Conductance in the voltage clamped case.
J Math Biol. 1978 Mar 3;5(2):121-42. doi: 10.1007/BF00275895.
7
[Mathematical model of electrogenic transport through biomembranes via oligomeric channels capable of conformational transitions].
Biofizika. 1979 Nov-Dec;24(6):1064-9.
8
Molecular aspects of electrical excitation in lipid bilayers and cell membranes.
Horiz Biochem Biophys. 1976;2:230-84.
9
A parametric modeling of membrane current fluctuations with its application to the estimation of the kinetic properties of single ionic channels.
IEEE Trans Biomed Eng. 1989 Oct;36(10):1028-37. doi: 10.1109/10.40804.
10
The mechanism of the sodium pump.
Biochim Biophys Acta. 1980 Dec 31;604(3):321-45. doi: 10.1016/0005-2736(80)90577-5.
引用本文的文献
1
A Thermodynamic Model of Monovalent Cation Homeostasis in the Yeast Saccharomyces cerevisiae.
PLoS Comput Biol. 2016 Jan 27;12(1):e1004703. doi: 10.1371/journal.pcbi.1004703. eCollection 2016 Jan.
2
Effect of cytosolic pH on inward currents reveals structural characteristics of the proton transport cycle in the influenza A protein M2 in cell-free membrane patches of Xenopus oocytes.
PLoS One. 2014 Sep 11;9(9):e107406. doi: 10.1371/journal.pone.0107406. eCollection 2014.
3
Voltage-sensor transitions of the inward-rectifying K+ channel KAT1 indicate a latching mechanism biased by hydration within the voltage sensor.
Plant Physiol. 2014 Oct;166(2):960-75. doi: 10.1104/pp.114.244319. Epub 2014 Sep 2.
4
Mechanisms of fusicoccin action: A dominant role for secondary transport in a higher-plant cell.
Planta. 1988 May;174(2):187-200. doi: 10.1007/BF00394771.
5
Rectification of the channelrhodopsin early conductance.
Biophys J. 2011 Sep 7;101(5):1057-68. doi: 10.1016/j.bpj.2011.07.040.
6
Two open states with progressive proton selectivities in the branched channelrhodopsin-2 photocycle.
Biophys J. 2010 Mar 3;98(5):753-61. doi: 10.1016/j.bpj.2009.10.052.
7
Channelrhodopsin-1 initiates phototaxis and photophobic responses in chlamydomonas by immediate light-induced depolarization.
Plant Cell. 2008 Jun;20(6):1665-77. doi: 10.1105/tpc.108.057919. Epub 2008 Jun 13.
8
Saturation and microsecond gating of current indicate depletion-induced instability of the MaxiK selectivity filter.
J Gen Physiol. 2007 Jul;130(1):83-97. doi: 10.1085/jgp.200709802.
9
Strengths and limits of Beta distributions as a means of reconstructing the true single-channel current in patch clamp time series with fast gating.
J Membr Biol. 2006 Apr;210(3):199-212. doi: 10.1007/s00232-006-0858-8. Epub 2006 Aug 14.
10
Ion channels in Arabidopsis plasma membrane : transport characteristics and involvement in light-induced voltage changes.
Plant Physiol. 1992 May;99(1):96-102. doi: 10.1104/pp.99.1.96.
本文引用的文献
1
Generalized kinetic analysis of ion-driven cotransport systems: a unified interpretation of selective ionic effects on Michaelis parameters.
J Membr Biol. 1984;77(2):123-52. doi: 10.1007/BF01925862.
2
Kinetic properties of ion carriers and channels.
J Membr Biol. 1980 Dec 30;57(3):163-78(-RETURN-). doi: 10.1007/BF01869585.
3
Electrogenic Cl- pump in Acetabularia.
Philos Trans R Soc Lond B Biol Sci. 1982 Dec 1;299(1097):447-57. doi: 10.1098/rstb.1982.0143.
4
Thermodynamic and kinetic properties of electrogenic ion pumps.
Biochim Biophys Acta. 1984 Sep 3;779(3):307-41. doi: 10.1016/0304-4157(84)90015-7.
5
New looks and outlooks on physical enzymology.
Q Rev Biophys. 1968 May;1(1):3-33. doi: 10.1017/s0033583500000445.
6
Ionic blockage of sodium channels in nerve.
J Gen Physiol. 1973 Jun;61(6):687-708. doi: 10.1085/jgp.61.6.687.
7
The mechanistic nature of the membrane potential dependence of sodium-sugar cotransport in small intestine.
J Membr Biol. 1985;87(2):159-72. doi: 10.1007/BF01870662.
8
Steady-state kinetic analysis of an electroenzyme.
Biochem Soc Symp. 1985;50:11-29.
9
Microscopic description of voltage effects on ion-driven cotransport systems.
J Membr Biol. 1986;91(3):275-84. doi: 10.1007/BF01868820.
10
Generalized kinetic analysis of ion-driven cotransport systems: II. Random ligand binding as a simple explanation for non-michaelian kinetics.
J Membr Biol. 1986;90(1):67-87. doi: 10.1007/BF01869687.
Zotero 插件