School of Chemistry, Madurai Kamaraj University, Madurai 625021, India.
School of Chemistry, Madurai Kamaraj University, Madurai 625021, India.
Spectrochim Acta A Mol Biomol Spectrosc. 2014 Apr 5;123:18-24. doi: 10.1016/j.saa.2013.12.054. Epub 2013 Dec 18.
A fluorimetric sensor for Hg(2+) ion and Cysteine based on quinazoline platform was designed and synthesized by one step reaction and characterized by using common spectroscopic methods. Time Dependent Density Functional Theory calculations shows that probe behaves as "ON-OFF" fluorescent quenching sensor via electron transfer/heavy atom effect. Receptor was found to exhibit selective fluorescence quenching behavior over the other competitive metal ions, and also the receptor-Hg(2+) ensemble act as an efficient "OFF-ON" sensor for Cysteine. Moreover this sensor has also been successfully applied to detection of Hg(2+) in natural water samples with good recovery.
基于喹唑啉平台，设计并合成了一种用于 Hg(2+)离子和半胱氨酸的荧光传感器，通过一步反应得到，并通过常见的光谱方法进行了表征。时变密度泛函理论计算表明，探针通过电子转移/重原子效应表现为“开-关”荧光猝灭传感器。发现该受体对其他竞争金属离子表现出选择性荧光猝灭行为，而受体-Hg(2+)配合物则可以作为半胱氨酸的有效“关-开”传感器。此外，该传感器还成功地应用于天然水样中 Hg(2+)的检测，回收率良好。
