Uchino J, Hata Y, Shinada Y, Sasaki F, Kasai Y, Itoh F
Chir Pediatr. 1978;19(1):33-7.
An analysis was made from a histopathological and clinical standpoint of 6 cases of yolk sac tumor over a period of 15 years, treated in the first surgical department of the University of Hokkaido. All these cases, with the exception of one retroperitoneal tumor, were diagnosed as embryonic carcinomas before the study. AFP were examined throughout the duration of treatment and their levels reflected changes corresponding to the effects of treatment and recurrence. They were seen in the form of special fluorescence in the tumor cells using the antibody immunofluorescence method. Radiotherapy and chemotherapy may be effective, but the prognosis of these tumors is poor. Amongst the cases mentioned, only the child with a tumor of testicular origin is in good health.
从组织病理学和临床角度对北海道大学第一外科在15年间治疗的6例卵黄囊瘤进行了分析。除1例腹膜后肿瘤外，所有这些病例在研究前均被诊断为胚胎癌。在整个治疗期间检测了甲胎蛋白（AFP），其水平反映了与治疗效果和复发相对应的变化。使用抗体免疫荧光法在肿瘤细胞中可见其呈特殊荧光形式。放疗和化疗可能有效，但这些肿瘤的预后较差。在上述病例中，只有一名睾丸源性肿瘤患儿健康状况良好。
