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[关于EQ-5D葡萄牙语版本验证的贡献]

[Contribution for the validation of the Portuguese version of EQ-5D].

作者信息

Ferreira Pedro Lopes, Ferreira Lara Noronha, Pereira Luis Nobre

机构信息

Faculdade de Economia. Universidade de Coimbra. Coimbra. Portugal. & Centro de Estudos e Investigação em Saúde da Universidade de Coimbra. Coimbra. Portugal.

Escola Superior de Gestão, Hotelaria e Turismo. Universidade do Algarve. Faro. Portugal. & Centro de Estudos e Investigação em Saúde da Universidade de Coimbra. Coimbra. Portugal.

出版信息

Acta Med Port. 2013 Nov-Dec;26(6):664-75. Epub 2013 Dec 20.

Abstract

INTRODUCTION

The EQ-5D allows the achievement of two essential components of any measure of health-related quality of life to be used in cost-utility economic evaluations: (i) a profile describing the health status in terms of domains or dimensions; and (ii) a numeric value associated with the health status described.

AIM

The Portuguese version of the EQ-5D questionnaire was completed in 1998, based on guidelines set by the EuroQol Group, including translation and back translation procedures. Despite its wide use in Portugal, until now it had not yet been published studies that initially led to the Portuguese version and the guarantee of acceptability, reliability and validity. The purpose of this article is to document these first values relating to the Portuguese version of the EQ-5D.

MATERIAL AND METHODS

We used three different samples: a first one with 1,500 individuals representative of the Portuguese population; a second with 140 individuals just intended for the reliability test; and a third sample with 643 individual patients with cataracts, asthma, chronic obstructive pulmonary disease, or rheumatoid arthritis.

RESULTS

The acceptability was assessed by the number of missing responses. It was also found a marked ceiling effect, with a large part of the sample not reporting any problems in the dimensions of the EQ-5D.

DISCUSSION

The construct validity was tested by examining the degree to which low values of EQ-5D were positively associated with increasing age, being female, and the sick, as well as the values of dimensions of the SF-36v2 scale. Convergent validity was based on correlations between EQ-5D values and other specific measures. The EQ-5D showed moderate to high correlations with other disease-specific measures of health status and health related quality of life.

CONCLUSION

We can state that the Portuguese version of the EQ-5D has a good accessibility, reliability and validity in measuring health.

摘要

引言

EQ-5D能够实现用于成本效用经济评估的任何健康相关生活质量衡量指标的两个基本组成部分:(i)一个根据领域或维度描述健康状况的概况;以及(ii)与所描述的健康状况相关的数值。

目的

EQ-5D问卷的葡萄牙语版本于1998年完成,依据欧洲生活质量小组制定的指南,包括翻译和回译程序。尽管其在葡萄牙广泛使用,但截至目前,尚未有研究发表最初导致该葡萄牙语版本产生以及对其可接受性、可靠性和有效性的保证。本文的目的是记录与EQ-5D葡萄牙语版本相关的这些初始数值。

材料与方法

我们使用了三个不同的样本:第一个样本有1500名代表葡萄牙人口的个体;第二个样本有140名仅用于可靠性测试的个体;第三个样本有643名患有白内障、哮喘、慢性阻塞性肺疾病或类风湿关节炎的个体患者。

结果

通过缺失回答的数量评估可接受性。还发现了明显的天花板效应,样本中的很大一部分在EQ-5D的维度上未报告任何问题。

讨论

通过检查EQ-5D低值与年龄增长、女性以及患病情况呈正相关的程度,以及SF-36v2量表维度的值,来测试结构效度。收敛效度基于EQ-5D值与其他特定测量之间的相关性。EQ-5D与其他特定疾病的健康状况和健康相关生活质量测量显示出中度至高相关性。

结论

我们可以说,EQ-5D的葡萄牙语版本在测量健康方面具有良好的可及性、可靠性和有效性。

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