Zheng Xiaozuo, Kang Kai, Li Tong, Lu Bo, Dong Jiangtao, Gao Shijun
Department of Orthopedics, Third Hospital of Hebei Medical University, 139 Ziqiang Road, Shijiazhuang, 050051, Hebei, People's Republic of China,
Eur J Orthop Surg Traumatol. 2014 Dec;24(8):1513-23. doi: 10.1007/s00590-013-1400-1. Epub 2014 Jan 4.
The aim of this up-to-date meta-analysis was to compare the effects of surgical versus non-surgical treatment of patients following primary patellar dislocation and to provide the best evidence currently available. A comprehensive literature search was conducted using multiple databases, including Medline, Embase, and Cochrane Registry of Clinical Trials. All databases were searched from the earliest records to May 2013. Eligible studies were selected, and data were extracted by two independent investigators. The primary outcome variable was the frequency of recurrent patellar dislocation. The other outcomes included knee function scores, patient-rated outcomes, and radiographic examination. If appropriate, meta-analysis of these variables was performed. Nine independent trials were found to match the inclusion criteria. The pooled results demonstrated that the incidence of recurrent patellar dislocation and Hughston visual analog scale was significantly lower in the surgical treatment group than that in the non-surgical treatment group (P < 0.05). There was no statistically significant difference between the two treatment groups in frequency of subsequent surgical interventions, percentage of excellent or good subjective opinion, Kujala score, pain score on visual analog scale, and severity of patellofemoral joint osteoarthrosis (P > 0.05). This up-to-date meta-analysis indicates that surgical treatment was associated with a lower risk of recurrent patellar dislocation, but a lower Hughston VAS than non-surgical treatment for primary patellar dislocation. More large high-quality trials and further studies are needed to overcome the limitations of small sample sizes, and varieties of different surgical procedures or non-surgical management strategies adopted in the included trials.
这项最新的荟萃分析旨在比较初次髌骨脱位患者手术治疗与非手术治疗的效果,并提供目前可得的最佳证据。使用多个数据库进行了全面的文献检索,包括医学索引数据库(Medline)、荷兰医学文摘数据库(Embase)和考克兰临床试验注册库。所有数据库均从最早记录检索至2013年5月。筛选出符合条件的研究,并由两名独立研究人员提取数据。主要结局变量是髌骨复发性脱位的频率。其他结局包括膝关节功能评分、患者自评结局和影像学检查。如有合适情况,对这些变量进行荟萃分析。发现有9项独立试验符合纳入标准。汇总结果表明,手术治疗组髌骨复发性脱位的发生率和休斯顿视觉模拟量表评分显著低于非手术治疗组(P < 0.05)。两组在后续手术干预频率、优秀或良好主观意见的百分比、库亚拉评分、视觉模拟量表疼痛评分以及髌股关节骨关节炎严重程度方面无统计学显著差异(P > 0.05)。这项最新的荟萃分析表明,手术治疗与较低的髌骨复发性脱位风险相关,但对于初次髌骨脱位,手术治疗的休斯顿视觉模拟量表评分低于非手术治疗。需要更多大型高质量试验和进一步研究来克服样本量小以及纳入试验中采用的不同手术程序或非手术管理策略种类多样的局限性。