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人雪旺细胞:体内外的细胞化学、超微结构及免疫学研究

Human Schwann cells: cytochemical, ultrastructural and immunological studies in vivo and in vitro.

作者信息

Scarpini E, Meola G, Baron P L, Beretta S, Velicogna M, Moggio M, Buscaglia M, Doronzo R, Scarlato G

出版信息

Basic Appl Histochem. 1987;31(1):33-42.

PMID:2439063
Abstract

Cytochemical, ultrastructural and immunological properties of human Schwann cells were studied in normal adult and foetal nerve sections and in tissue cultures. As specific markers for Schwann cells we used S-100 protein and laminin. The presence of Sudan black-positive, Oil Red-O-negative material was found in Schwann cells in vitro. Structural features, examined at E.M. level, are described. This information may be useful in nerve tissue culture studies, a new tool for the investigation of dyschwannian neuropathies.

摘要

在正常成人和胎儿神经切片以及组织培养物中研究了人雪旺细胞的细胞化学、超微结构和免疫学特性。我们使用S-100蛋白和层粘连蛋白作为雪旺细胞的特异性标志物。在体外雪旺细胞中发现了苏丹黑阳性、油红O阴性物质。描述了在电子显微镜水平检查的结构特征。这些信息可能对神经组织培养研究有用,神经组织培养是研究雪旺细胞异常性神经病的一种新工具。

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