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体力要求高的工作与早产:一项系统评价和荟萃分析

Physically demanding work and preterm delivery: a systematic review and meta-analysis.

作者信息

van Beukering M D M, van Melick M J G J, Mol B W, Frings-Dresen M H W, Hulshof C T J

机构信息

Department of Occupational Health and Safety Service, DNV GL, P.O. Box 9035, 6800 ET, Arnhem, The Netherlands,

出版信息

Int Arch Occup Environ Health. 2014 Nov;87(8):809-34. doi: 10.1007/s00420-013-0924-3. Epub 2014 Jan 4.

Abstract

OBJECTIVE

Physically demanding work may increase the risk of preterm delivery (PTD), defined as delivery before 37 weeks. We assessed the available evidence.

METHODS

A systematic search in Medline, Embase and Nioshtic for the period 1990 to June 2012 for observational and intervention studies on physically demanding work (prolonged standing, heavy lifting, physical exertion, occupational fatigue and demanding posture) and PTD. Selected studies were assessed for their risk of bias and pooled using a random effects model. Results of case-control and cohort studies were reported separately in subgroups.

RESULTS

We found 10 studies with low risk of bias and seven studies with moderate risk of bias. Standing and walking at work during pregnancy for more than 3 h per day was associated with an increased risk for PTD [OR 1.3 (95% CI 1.1-1.6)], just as lifting and carrying >5 kg [OR 1.3 (95% CI 1.05-1.6)] or lifting and carrying in the third trimester of the pregnancy [OR 1.3 (95% CI 1.01-1.8)]. Jobs that required physical effort or physical exertion were associated with an increased risk of PTD [OR 1.4 (95% CI 1.19-1.66)]. Working during pregnancy in jobs with a combination of two or more physical tasks, physical effort or occupational fatigue was also associated with an increased risk of PTD [OR 1.5 (95% CI 1.1-2.0)].

CONCLUSIONS

Physically demanding work during pregnancy is associated with an increased risk of PTD, especially in jobs with a combination of tasks with physical effort. In general, only small to moderate elevations of risks were found.

摘要

目的

体力要求高的工作可能会增加早产(定义为妊娠37周前分娩)风险。我们评估了现有证据。

方法

对1990年至2012年6月期间的Medline、Embase和Nioshtic进行系统检索,查找关于体力要求高的工作(长时间站立、重物搬运、体力消耗、职业疲劳和费力姿势)与早产的观察性和干预性研究。对所选研究进行偏倚风险评估,并使用随机效应模型进行汇总。病例对照研究和队列研究的结果在亚组中分别报告。

结果

我们发现10项偏倚风险低的研究和7项偏倚风险中等的研究。孕期每天工作时站立和行走超过3小时与早产风险增加相关[比值比(OR)1.3(95%置信区间[CI]1.1 - 1.6)],搬运超过5千克重物[OR 1.3(95% CI 1.05 - 1.6)]或在妊娠晚期搬运重物[OR 1.3(95% CI 1.01 - 1.8)]也如此。需要体力或体力消耗的工作与早产风险增加相关[OR 1.4(95% CI 1.19 - 1.66)]。孕期从事包含两项或更多体力任务、体力消耗或职业疲劳的工作也与早产风险增加相关[OR 1.5(95% CI 1.1 - 2.0)]。

结论

孕期体力要求高的工作与早产风险增加相关,尤其是在包含体力任务组合的工作中。总体而言,仅发现风险有小到中度升高。

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