Rahman R, Stephenson J
Calderdale Royal Hospital, Halifax, UK.
School of Human and Health Sciences, University of Huddersfield, Queensgate, UK.
Eye (Lond). 2014 Apr;28(4):410-4. doi: 10.1038/eye.2013.305. Epub 2014 Jan 10.
To establish whether early vitrectomy for epiretinal membrane (ERM) is preferable to delayed surgery.
We carried out a retrospective study of 120 eyes from 120 patients with pre-operative visual acuity (VA) of 6/60 or better. Pre-operative logMAR score was considered to act as an appropriate proxy measure for time of surgical procedure, with scores of 0.3 or less considered to represent early surgery, scores of 0.4 or 0.5 considered to represent medium surgery, and scores of 0.6 or more considered to represent late surgery for ERM. Patients were either pseudophakic at the time of vitrectomy or underwent combined phaco-vitrectomy for symptomatic ERM.
Evaluation of parameter coefficients indicated that controlling for other factors, a delay of the surgical procedure from a state of early to medium corresponded to an increase (ie, disbenefit) of 0.074 units in post-operative logMAR score (95% confidence interval -0.001-0.15). A delay of the surgical procedure from a state of early to late corresponded to an increase (ie, disbenefit) of 0.21 units in post-operative logMAR score (95% confidence interval 0.13-0.29). Mean post-operative VA for early surgery was 0.16, out of which 36.2% of patients had a LogMAR score of 0.1 or better. This is in comparison to 17.2% in late ERM (those with a pre-operative logMAR score of 0.6 or more).
We conclude that early surgery is associated with a lower (ie, better) post-operative logMAR score. Vitrectomy for early symptomatic ERM, in carefully selected patients, is beneficial in preserving excellent vision and allows quicker visual rehabilitation.
确定视网膜前膜(ERM)早期玻璃体切除术是否优于延迟手术。
我们对120例术前视力(VA)为6/60或更好的患者的120只眼进行了回顾性研究。术前LogMAR评分被视为手术时间的合适替代指标,评分0.3或更低被视为代表早期手术,评分0.4或0.5被视为代表中期手术,评分0.6或更高被视为代表ERM的晚期手术。患者在玻璃体切除时要么是人工晶状体眼,要么因有症状的ERM接受了白内障超声乳化联合玻璃体切除术。
参数系数评估表明,在控制其他因素的情况下,手术从早期延迟到中期,术后LogMAR评分增加(即不利)0.074个单位(95%置信区间-0.001-0.15)。手术从早期延迟到晚期,术后LogMAR评分增加(即不利)0.21个单位(95%置信区间0.13-0.29)。早期手术的术后平均视力为0.16,其中36.2%的患者LogMAR评分为0.1或更好。相比之下,晚期ERM患者(术前LogMAR评分0.6或更高)的这一比例为17.2%。
我们得出结论,早期手术与较低(即更好)的术后LogMAR评分相关。对于精心挑选的有症状早期ERM患者,玻璃体切除术有利于保留极佳视力并能更快实现视力恢复。