Dawson S R, Shunmugam M, Williamson T H
Department of Ophthalmology, St. Thomas' Hospital, London, UK.
Eye (Lond). 2014 Feb;28(2):219-24. doi: 10.1038/eye.2013.253. Epub 2013 Dec 6.
Pars plana vitrectomy (PPV) is commonly used to remove the epiretinal membrane (ERM), but the timing of surgical intervention guided by visual acuity (VA) performance at presentation is uncertain.
Prospectively entered clinical data of 237 patients on an electronic patient record from 2001 to 2011 were analysed to determine visual outcomes, in particular in relation to pre-operative VA.
The mean age of the patients was 68.8 years and 54.4% were female. Median follow-up was 0.55 years. The median pre-operative logMAR VA was 0.60 (SD 0.48-0.78, Snellen equivalent 6/36) and post-operative VA was 0.30 (SD 0.18-0.60, 6/12, P<0.005). Pre-operative VA correlated with post-operative VA (linear R(2)=0.22, P<0.0001). In all, 69.6% of patients showed an improvement in VA, 15.2% showed no change, and the condition of 15.2% worsened. The number of patients with an improvement in logMAR VA of more than 0.3 was greatest in those who had a pre-operative VA of 1.0 (6/60) or worse, followed by those in the range of 0.6-0.9 and then those with pre-operative VA of 0.5 or better (P<0.001). The proportion of patients with visual improvement of logMAR VA of more than 0.3 increased statistically with progressing years (P=0.019).
In conclusion, this study shows improvement in VA after PPV and ERM removal. Patients with better initial VA achieve higher levels of visual outcome but those with poorer pre-operative VA show a greater change in VA following ERM surgery. Results of surgery improved over the time period of the study.
玻璃体切割术(PPV)常用于去除视网膜前膜(ERM),但根据就诊时视力(VA)表现来指导手术干预的时机尚不确定。
分析了2001年至2011年期间前瞻性录入电子病历的237例患者的临床数据,以确定视力结果,尤其是与术前视力的关系。
患者的平均年龄为68.8岁,女性占54.4%。中位随访时间为0.55年。术前logMAR视力的中位数为0.60(标准差0.48 - 0.78,Snellen等效值6/36),术后视力为0.30(标准差0.18 - 0.60,6/12,P<0.005)。术前视力与术后视力相关(线性R² = 0.22,P<0.0001)。总体而言,69.6%的患者视力有所改善,15.2%无变化,15.2%的病情恶化。术前视力为1.0(6/60)或更差的患者中,logMAR视力改善超过0.3的人数最多,其次是视力在0.6 - 0.9范围内的患者,然后是术前视力为0.5或更好的患者(P<0.001)。logMAR视力改善超过0.3的患者比例随时间推移有统计学意义的增加(P = 0.019)。
总之,本研究表明PPV和ERM切除术后视力有所改善。初始视力较好的患者视力结果更高,但术前视力较差的患者在ERM手术后视力变化更大。在研究期间,手术结果有所改善。