de Almeida Camila Rodrigues, Carneiro Kennedy, Fiorelli Rossano, Orsini Marco, Alvarenga Regina Maria Papais
Neurology Department, Center of Biological and Health Sciences , State University of Rio de Janeiro (UNIRIO).
Science Rehabilitation, University Center Augusto Motta (UNISUAM) , Rio de Janeiro, Brazil.
Neurol Int. 2013 Nov 11;5(4):e23. doi: 10.4081/ni.2013.e23. eCollection 2013.
The aim of the present study is to describe the type and frequency of bladder dysfunction in a series of female patients with multiple sclerosis (MS) from Rio de Janeiro, and analyze the role of the urologist in the multidisciplinary team. A team of urologists and a neurologist from the Hospital da Lagoa, Rio de Janeiro, Brazil, interviewed female patients with MS about illness onset, urologic follow-up since diagnosis, current stage of the disease and current urological symptoms. The interview was followed by an urodynamic testing, ultrasound of the urinary tract and urinalysis. Data resulting from the interviews and exam results were gathered and submitted to statistical evaluation. Sixty one patients were evaluated, with average age of 41.4 years. Urinary symptoms such as urinary incontinence, urinary hesitancy, urinary retention, urinary urgency and incomplete bladder emptying were reported in 44% of patients as initial signs of MS disease. Mean disease duration was 8 years and all patients (100%) with the primary progressive form of the disease and 63.5% with the relapsingremitting presentation had urological symptoms. Analysis of complementary exams showed that 37.7% of urinalysis, 8.2% of the urinary tract ultrasound exams and 66.7% of the urodynamic evaluations were abnormal and the most frequent abnormality were overactive neurogenic bladder. Only 4 patients (6.6%) had seen an urologist during the course of their disease and only 1.6% had performed an urodynamic evaluation. This study shows a high prevalence (68%) of urinary dysfunction in a female population with MS. Urologic care should be part of the multidisciplinary team since the beginning of the disease. An urodynamic evaluation and simple urinalysis should be included in the routine testing during disease follow-up due to the high incidence of neurogenic bladder and other urologic complications.
本研究旨在描述里约热内卢一系列多发性硬化症(MS)女性患者膀胱功能障碍的类型和频率,并分析泌尿科医生在多学科团队中的作用。巴西里约热内卢拉戈阿医院的一组泌尿科医生和一名神经科医生就疾病发作、诊断后的泌尿科随访、疾病当前阶段和当前泌尿系统症状对MS女性患者进行了访谈。访谈之后进行了尿动力学检测、泌尿系统超声检查和尿液分析。收集了访谈和检查结果的数据并进行统计评估。共评估了61名患者,平均年龄为41.4岁。44%的患者报告有尿失禁、排尿犹豫、尿潴留、尿急和膀胱排空不全等泌尿系统症状,作为MS疾病的初始症状。平均病程为8年,所有原发性进行性疾病患者(100%)和63.5%复发缓解型患者有泌尿系统症状。补充检查分析显示,37.7%的尿液分析、8.2%的泌尿系统超声检查和66.7%的尿动力学评估异常,最常见的异常是神经源性膀胱过度活动。在疾病过程中,只有4名患者(6.6%)看过泌尿科医生,只有1.6%的患者进行过尿动力学评估。本研究表明,MS女性人群中泌尿系统功能障碍的患病率很高(68%)。从疾病一开始,泌尿科护理就应成为多学科团队的一部分。由于神经源性膀胱和其他泌尿系统并发症的发生率很高,在疾病随访期间的常规检查中应包括尿动力学评估和简单的尿液分析。