Akkoç Yeşim, Ersöz Murat, Yüceyar Nur, Tunç Hakan, Köklü Kurtuluş, Yoldaş Tahir Kurtuluş, Dönmez Ülkü, Uzunköprü Cihat, Alemdaroğlu Ebru, Bilen Şule, Emre Ufuk, Özdolap Şenay, Tuncay Elif, Yücesan Canan, Gök Haydar, Ercan Merve Bahar, Uygunol Kürşat, Koçer Belgin, Zinnuroğlu Murat
a Department of Physical Medicine and Rehabilitation , Ege University Faculty of Medicine , Bornova - İzmir , Turkey.
b Department of Physical Medicine and Rehabilitation , Ankara Physical Medicine and Rehabilitation Education and Research Hospital , Ankara , Turkey.
J Spinal Cord Med. 2016;39(2):229-33. doi: 10.1179/2045772315Y.0000000021. Epub 2016 Feb 15.
To determine the frequency and severity as well as the diagnosis and treatment of overactive bladder problems in patients with multiple sclerosis (MS) followed up at five centers in Turkey.
Survey study.
Outpatient tertiary clinics of physical medicine and rehabilitation and neurology.
Consecutive MS patients scheduled for outpatient follow-up (n = 309).
MS patients were asked to complete a questionnaire regarding the frequency and severity, as well as the diagnosis and treatment of their overactive bladder problems.
The mean age ± SD was 39.3 ± 10.6 years. Urinary urgency was the most common urinary symptom (62%), followed by frequency (50.4%), urge incontinence (44.7%) and nocturia (33%). Residual urine volume was measured using a portable ultrasound instrument in 13.3% of the patients and by catheterization in 16.2% of them. Urodynamic investigations and urinary tract ultrasound were performed on 26.5% and 35.3% of the patients, respectively. Anticholinergic medications were prescribed for 27.5% of the patients. Intermittent catheterization and indwelling catheterization were used on 8.1% and 1.9% of the patients, respectively. The overactive bladder symptom score (OABSS) was significantly higher in patients who had had residual urine measurement (P < 0.001), upper urinary tract assessment by ultrasound (P < 0.001), urodynamic assessment (P < 0.001), admitted to a doctor for urinary symptoms (P < 0.001), and current or past catheter use (P = 0.002).
Urgency was the most common urinary symptom followed by frequency, urge incontinence and nocturia in MS patients. The patients with lower OABSS had detailed urological assessments less frequently than the patients with higher OABSS.
确定在土耳其五个中心接受随访的多发性硬化症（MS）患者膀胱过度活动症问题的发生率、严重程度以及诊断和治疗情况。
调查研究。
物理医学与康复及神经科的门诊三级诊所。
计划进行门诊随访的连续MS患者（n = 309）。
要求MS患者填写一份关于膀胱过度活动症问题的发生率、严重程度以及诊断和治疗情况的问卷。
平均年龄±标准差为39.3±10.6岁。尿急是最常见的泌尿系统症状（62%），其次是尿频（50.4%）、急迫性尿失禁（44.7%）和夜尿症（33%）。13.3%的患者使用便携式超声仪器测量残余尿量，16.2% 的患者通过导尿测量。分别有26.5%和35.3%的患者进行了尿动力学检查和泌尿系统超声检查。27.5%的患者开具了抗胆碱能药物。分别有8.1%和1.9%的患者使用间歇性导尿和留置导尿。进行了残余尿量测量的患者（P < 0.001）、通过超声进行上尿路评估的患者（P < 0.001）、进行了尿动力学评估的患者（P < 0.001）、因泌尿系统症状就医的患者（P < 0.001）以及目前或过去使用过导尿管的患者（P = 0.002）的膀胱过度活动症症状评分（OABSS）显著更高。
尿急是MS患者中最常见的泌尿系统症状，其次是尿频、急迫性尿失禁和夜尿症。膀胱过度活动症症状评分较低的患者比评分较高的患者接受详细泌尿系统评估的频率更低。
