Gomez-Millan Jaime, Fernández Jesús Romero, Medina Carmona Jose Antonio
Servicio de Oncologia Radioterapica del Hospital Clínico Virgen de la Victoria, Campus Teatinos s/n, 29010 Málaga, Spain.
Department of Radiation Oncology, Hospital Puerta de Hierro, Calle de Manuel de Falla, 1, 28222 Majadahonda, Madrid, Spain.
Rep Pract Oncol Radiother. 2013 Oct 20;18(6):371-5. doi: 10.1016/j.rpor.2013.09.008.
IMRT provides highly conformal dose distributions creating non uniform spatial intensity using different segments in the beam.
MATERIAL & METHODS AND RESULTS: Different retrospective studies have shown a high capability of IMRT to treat tumours close to the base of skull. Prospective studies have shown a decrease in xerostomia compared with conventional 3D conformal treatment (3DCRT). Modulation of intensity is performed by the movement of the multileaf collimator (MLC) that can deliver the radiation in different ways, such as static field segments, dynamic field segments and rotational delivery (arc therapy and tomotherapy). There are slight differences among the different techniques in terms of homogeneity, dose conformity and treatment delivery time.
The best method to deliver IMRT will depend on multiple factors such as deliverability, practicality, user training and plan quality.
调强放射治疗（IMRT）利用射束中的不同射野段产生高度适形的剂量分布，形成不均匀的空间强度。
不同的回顾性研究表明，IMRT在治疗靠近颅底的肿瘤方面具有很高的能力。前瞻性研究表明，与传统的三维适形放疗（3DCRT）相比，口干燥症有所减少。强度调制通过多叶准直器（MLC）的移动来实现，MLC可以以不同方式输送辐射，如静态射野段、动态射野段和旋转输送（弧形治疗和断层放射治疗）。不同技术在均匀性、剂量适形性和治疗输送时间方面存在细微差异。
实施IMRT的最佳方法将取决于多个因素，如可输送性、实用性、用户培训和计划质量。
