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接受调强放射治疗的头颈癌患者的生活质量、焦虑和抑郁情况

Quality of Life, Anxiety, and Depression in the Head-and-Neck Cancer Patients, Undergoing Intensity-Modulated Radiotherapy Treatment.

作者信息

Nikoloudi Maria, Lymvaios Ioannis, Zygogianni Anna, Parpa Efi, Strikou Dimitra-Aspasia, Tsilika Eleni, Kouloulias Vassilios, Mystakidou Kyriaki

机构信息

Department of Radiology, Pain Relief and Palliative Care Unit, School of Medicine, Areteion Hospital, National and Kapodistrian University of Athens, Corinthia, Greece.

Unit of Thalassemia, General Hospital of Corinthia, Corinthia, Greece.

出版信息

Indian J Palliat Care. 2020 Jan-Mar;26(1):54-59. doi: 10.4103/IJPC.IJPC_168_19. Epub 2020 Jan 28.

DOI:10.4103/IJPC.IJPC_168_19
PMID:32132785
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7017687/
Abstract

AIMS

The aim of this study is to investigate and compare distress and quality-of-life parameters among head-and-neck cancer patients who underwent intensity-modulated radiotherapy (IMRT).

SUBJECTS AND METHODS

The patients' sample consists of 55 individuals under IMRT treatment. Three questionnaires (Quality of Life Questionnaire [QLQ]-C30 and QLQ-H and N35) of the European Organization for the Research and Treatment of Cancer and the Greek Hospital Anxiety and Depression Scales were used.

RESULTS

Functioning and symptoms scales measured a week before the scheduled treatment worsen significantly until the end of the treatment and at the 3-month follow-up, tend to revert to their pretreatment values.

CONCLUSIONS

Our results showed that all parameters (functioning scales, symptoms scales, and G-HAD subscales) worsen from the start to the end treatment and tend to revert to their pretreatment values after a 3-month period.

摘要

目的

本研究旨在调查和比较接受调强放射治疗（IMRT）的头颈癌患者的痛苦程度和生活质量参数。

受试者与方法

患者样本包括55名接受IMRT治疗的个体。使用了欧洲癌症研究与治疗组织的三份问卷（生活质量问卷[QLQ]-C30以及QLQ-H和N35）和希腊医院焦虑与抑郁量表。

结果

在预定治疗前一周测量的功能和症状量表在治疗结束时及3个月随访时显著恶化，之后趋于恢复到治疗前的值。

结论

我们的结果表明，所有参数（功能量表、症状量表和G-HAD子量表）从治疗开始到结束时均恶化，并在3个月后趋于恢复到治疗前的值。