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孕期打鼾及其与嗜睡和妊娠结局的关系——一项前瞻性研究。

Snoring during pregnancy and its relation to sleepiness and pregnancy outcome - a prospective study.

作者信息

Sarberg Maria, Svanborg Eva, Wiréhn Ann-Britt, Josefsson Ann

机构信息

Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Department of Obstetrics and Gynecology in Linköping, County Council of Östergötland, Linköping, Sweden.

出版信息

BMC Pregnancy Childbirth. 2014 Jan 13;14:15. doi: 10.1186/1471-2393-14-15.

Abstract

BACKGROUND

The incidence of snoring and sleepiness is known to increase during pregnancy, and this might impact maternal health and obstetric outcome. However, the association between snoring and sleepiness during pregnancy is not fully understood. This study was aimed at investigating the development of snoring during pregnancy and prospectively assessing if there is an association between snoring and sleepiness or adverse pregnancy outcomes, such as preeclampsia, mode of delivery, and fetal complications.

METHODS

Consecutively recruited pregnant women (n = 500) received a questionnaire concerning snoring and sleep at the 1st and 3rd trimester of pregnancy. The women who had rated their frequency of snoring at both occasions (n = 340) were divided into subgroups according to the development of snoring they reported and included in the subsequent analyses. Additional medical data were collected from the medical records.

RESULTS

The frequency of snoring was 7.9% in the 1st trimester and increased to 21.2% in the 3rd trimester of pregnancy. The women who snored already in early pregnancy had significantly higher baseline BMI (p = 0.001) than the women who never snored, but snoring was not associated with the magnitude of weight gain during pregnancy. Snoring women were more likely to experience edema in late pregnancy than the non-snorers. Women who started to snore during pregnancy had higher Epworth Sleepiness Scores than the non snorers in both early and late pregnancy. No significant association between obstetric outcome and snoring was found.

CONCLUSION

Snoring does increase during pregnancy, and this increase is associated with sleepiness, higher BMI at the start of pregnancy and higher prevalence of edema, but not with weight gain.

摘要

背景

已知孕期打鼾和嗜睡的发生率会增加,这可能会影响孕产妇健康和产科结局。然而,孕期打鼾与嗜睡之间的关联尚未完全明确。本研究旨在调查孕期打鼾情况,并前瞻性评估打鼾与嗜睡或不良妊娠结局(如先兆子痫、分娩方式和胎儿并发症)之间是否存在关联。

方法

连续招募500名孕妇,在妊娠第1和第3孕期接受关于打鼾和睡眠的问卷调查。在两个阶段均对打鼾频率进行评分的妇女(n = 340),根据她们报告的打鼾发展情况分为亚组,并纳入后续分析。从病历中收集其他医学数据。

结果

妊娠第1孕期打鼾频率为7.9%,在第3孕期增至21.2%。妊娠早期就打鼾的妇女的基线BMI显著高于从不打鼾的妇女(p = 0.001),但打鼾与孕期体重增加幅度无关。打鼾的妇女在妊娠晚期比不打鼾的妇女更容易出现水肿。孕期开始打鼾的妇女在妊娠早期和晚期的爱泼华嗜睡量表得分均高于不打鼾的妇女。未发现产科结局与打鼾之间存在显著关联。

结论

孕期打鼾确实会增加,且这种增加与嗜睡、妊娠开始时较高的BMI以及较高的水肿发生率有关,但与体重增加无关。

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