Center for Perinatal Studies, Swedish Medical Center, 1124 Columbia Street, Suite 750, Seattle, WA 98104, USA.
Sleep Breath. 2013 May;17(2):541-7. doi: 10.1007/s11325-012-0717-z. Epub 2012 Aug 21.
Mounting evidence implicate habitual snoring, a prominent symptom of sleep-disordered breathing, as an important risk factor for adverse pregnancy outcomes including preeclampsia and gestational diabetes. Little, however, is known about the determinants of habitual snoring among pregnant women. We sought to assess its prevalence and to identify maternal characteristics associated with habitual snoring during pregnancy.
Pregnant women (N = 1,303) receiving prenatal care provided information about habitual snoring before and during pregnancy in in-person interviews completed in early pregnancy. We calculated adjusted odds ratios (aOR) and 95 % confidence intervals (95 % CI) from multivariable models designed to identify factors associated with snoring during pregnancy.
Approximately 7.3 % of pregnant women reported habitual snoring during early pregnancy. The odds of habitual snoring during pregnancy was strongly related with maternal reports of habitual snoring prior to the index pregnancy (aOR = 24.32; 95 % CI, 14.30-41.51). Advanced maternal age (≥35 years) (aOR = 2.02; 95 % CI, 1.11-3.68), history of pregestational diabetes (aOR = 3.61; 95 % CI, 1.07-12.2), history of mood and anxiety disorders (aOR = 1.81; 95 % CI, 1.02-3.20), and prepregnancy overweight (25-29.9 kg/m(2)) (aOR = 2.31; 95 % CI, 1.41-3.77) and obesity (≥30 kg/m(2)) (aOR = 2.81; 95 % CI, 1.44-5.48) status were statistically significant risk factors for habitual snoring during pregnancy. In addition, maternal smoking during pregnancy (aOR = 2.70; 95 % CI, 1.17-6.26) was associated with habitual snoring during pregnancy.
Identification of risk factors for habitual snoring during pregnancy has important implications for developing strategies aimed at reducing the prevalence of sleep-disordered breathing, promoting improved sleep hygiene and improved pregnancy outcomes among reproductive-age women.
越来越多的证据表明，习惯性打鼾是睡眠呼吸障碍的一个突出症状，也是子痫前期和妊娠期糖尿病等不良妊娠结局的重要危险因素。然而，人们对孕妇习惯性打鼾的决定因素知之甚少。我们试图评估其患病率，并确定与妊娠期间习惯性打鼾相关的产妇特征。
接受产前护理的孕妇（N=1303）在孕早期的面对面访谈中提供了关于孕前和孕期习惯性打鼾的信息。我们从多变量模型中计算了调整后的优势比（aOR）和 95%置信区间（95%CI），旨在确定与孕期打鼾相关的因素。
大约 7.3%的孕妇在孕早期报告习惯性打鼾。孕期习惯性打鼾的几率与孕妇在本次妊娠前报告的习惯性打鼾密切相关（aOR=24.32；95%CI，14.30-41.51）。高龄产妇（≥35 岁）（aOR=2.02；95%CI，1.11-3.68）、孕前糖尿病史（aOR=3.61；95%CI，1.07-12.2）、心境和焦虑障碍史（aOR=1.81；95%CI，1.02-3.20）、孕前超重（25-29.9kg/m²）（aOR=2.31；95%CI，1.41-3.77）和肥胖（≥30kg/m²）（aOR=2.81；95%CI，1.44-5.48）是孕期习惯性打鼾的统计学显著危险因素。此外，孕期吸烟（aOR=2.70；95%CI，1.17-6.26）与孕期习惯性打鼾相关。
确定孕期习惯性打鼾的危险因素对制定旨在降低睡眠呼吸障碍患病率、促进育龄妇女改善睡眠卫生和改善妊娠结局的策略具有重要意义。
