Mandal Sanjay Kumar, Ganguly Jacky, Mondal Soumya Sarathi, Sil Koelina
Department of Internal Medicine, Medical College, Kolkata, West Bengal, India.
BMJ Case Rep. 2014 Jan 13;2014:bcr2013201637. doi: 10.1136/bcr-2013-201637.
Autosomal dominant polycystic kidney disease (ADPKD) is well known for its different renal and extrarenal complications. Chronic renal failure (CRF) from ADPKD is also reported in older patients. On the other hand, multiple myeloma (MM) can also cause renal damage by different mechanisms. A 38-year-old man presented with dull aching abdominal pain, recent onset respiratory distress along with bilateral pedal swelling. Initial investigations revealed polycystic kidney disease but subsequently it was found that the patient was also suffering from MM. This rare association of ADPKD and MM was responsible for aggravating the renal damage and perhaps resulted in early age of presentation with CRF. The patient was managed symptomatically but unfortunately succumbed before starting specific treatment for MM.
常染色体显性多囊肾病（ADPKD）因其不同的肾脏和肾外并发症而闻名。老年患者中也有报道因ADPKD导致的慢性肾衰竭（CRF）。另一方面，多发性骨髓瘤（MM）也可通过不同机制导致肾损伤。一名38岁男性出现腹部隐痛、近期发作的呼吸窘迫以及双侧足部肿胀。初步检查显示为多囊肾病，但随后发现该患者还患有MM。ADPKD与MM这种罕见的关联加重了肾损伤，可能导致了CRF的早期出现。该患者接受了对症治疗，但不幸的是在开始针对MM的特异性治疗之前就去世了。
