The Joint Replacement Center, School of Medicine, Ewha Womans University, Seoul, Republic of Korea,
Int Orthop. 2014 Feb;38(2):297-303. doi: 10.1007/s00264-013-2243-4. Epub 2014 Jan 14.
The purpose of this prospective, randomised study was to evaluate long-term clinical results, radiographic findings, complications and revision and survivorship rates in patients <55 years at a minimum of 16 years after undergoing bilateral, sequential, simultaneous, cemented and cementless total knee arthroplasties (TKAs) in the same patients.
Bilateral, sequential, simultaneous TKAs were performed in 80 patients (160 knees). There were 63 women and 17 men with a mean age of 54.3 years (range 49-55), who received a cementless prosthesis in one knee and a cemented prosthesis in the other. The mean follow-up was 16.6 years (range 16-17).
At final review, the mean Knee Society (KS) knee scores (95.8 versus 96.9), Western Ontario and McMaster Universities (WOMAC) osteoarthritis (OA) index (25.4 versus 25.9), range of motion (ROM) (125° versus 128°), patient satisfaction (8.1 versus 8.3) and radiological results were similar in both groups. Femoral component survival rate was 100% in both groups at 17 years; at 17 years, the cemented tibial component survival rate was 100% and the cementless tibial component 98.7%. No osteolysis was identified in either group.
Long-term results of both cementless and cemented TKAs were encouraging in patients with OA who were <55 years. However, we found no evidence to prove the superiority of cementless over cemented TKAs.
本前瞻性、随机研究的目的是评估在同一位患者中,55 岁以下患者接受双侧、序贯、同期、骨水泥固定和非骨水泥固定全膝关节置换术(TKA)后至少 16 年的长期临床结果、影像学发现、并发症以及翻修率和生存率。
80 例(160 膝)患者接受了双侧、序贯、同期 TKA。其中 63 例为女性,17 例为男性,平均年龄 54.3 岁(范围 49-55),一侧膝关节接受非骨水泥假体,另一侧膝关节接受骨水泥假体。平均随访时间为 16.6 年(范围 16-17)。
末次随访时,膝关节学会(KS)膝关节评分(95.8 分比 96.9 分)、安大略西部和麦克马斯特大学(WOMAC)骨关节炎(OA)指数(25.4 分比 25.9 分)、活动度(125°比 128°)、患者满意度(8.1 分比 8.3 分)和影像学结果在两组间相似。两组在 17 年时股骨组件的生存率均为 100%;在 17 年时,骨水泥固定胫骨组件的生存率为 100%,非骨水泥固定胫骨组件的生存率为 98.7%。两组均未发现骨溶解。
对于 55 岁以下 OA 患者,骨水泥固定和非骨水泥固定 TKA 的长期结果令人鼓舞。然而,我们没有发现证据证明非骨水泥固定 TKA 优于骨水泥固定 TKA。