Franceschetti Edoardo, Torre Guglielmo, Palumbo Alessio, Papalia Rocco, Karlsson Jón, Ayeni Olufemi R, Samuelsson Kristian, Franceschi Francesco
Department of Orthopaedic and Trauma Surgery, Campus Bio-Medico University, Via Alvaro del Portillo, 200, 00128, Trigoria, Rome, Italy.
Department of Orthopaedics, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Knee Surg Sports Traumatol Arthrosc. 2017 Jun;25(6):1749-1756. doi: 10.1007/s00167-017-4519-5. Epub 2017 Mar 22.
The present piece of work provides improved knowledge about the evidence related to TKA in patients 60 years of age or younger, with special focus on fixation methods. Main concern of the review is to analyse the difference of survival rate and complications of cemented and cementless implants.
An electronic search was carried out between October and December 2015, through CINAHL, PubMed and the Cochrane Central Registry of Controlled Trials web databases. Articles in English, Italian, French and Spanish were considered for inclusion. Only peer-reviewed studies with adult patients aged 60 years or less, with diagnosis of osteoarthritis in more than 90% of the subjects, were considered for inclusion. All studies had to report outcomes after TKA with either cemented or cementless fixation technique.
No significant differences in terms of clinical, functional and radiological outcomes were found between cemented and cementless implants. Good clinical and functional results were obtained in terms of the Knee Society score and Western Ontario and McMaster Universities Osteoarthritis Index for both techniques. Radiographic results showed that radiolucent lines of <2 mm in width were detected at radiographs, without difference between cemented or cementless implants. Well-conducted trials on cemented versus cementless TKA were carried out in few papers. A survival rate of over 90% was reported in the majority of the studies at a mean follow-up of 8.6 years (range 5-18 years).
Similar results were observed in terms of functional outcome and survival rates for both cemented and cementless TKAs. High survival rates were reported for both operative techniques and cemented TKA did not offer additional benefit. Assuming that cementless prosthesis allows a stable fixation and reduces the time of operation, the authors recommend the cementless fixation as a primary choice in the investigated patient population. However, evidence is low, and further research is needed.
IV.
本研究旨在增进对60岁及以下患者全膝关节置换术(TKA)相关证据的了解,特别关注固定方法。本综述的主要关注点是分析骨水泥型和非骨水泥型植入物的生存率和并发症差异。
2015年10月至12月间,通过CINAHL、PubMed和Cochrane对照试验中央注册库网络数据库进行了电子检索。纳入英文、意大利文、法文和西班牙文的文章。仅纳入对60岁及以下成年患者进行的同行评审研究,且超过90%的受试者诊断为骨关节炎。所有研究都必须报告采用骨水泥型或非骨水泥型固定技术进行TKA后的结果。
骨水泥型和非骨水泥型植入物在临床、功能和放射学结果方面无显著差异。两种技术在膝关节协会评分以及西安大略和麦克马斯特大学骨关节炎指数方面均取得了良好的临床和功能结果。影像学结果显示,X线片上检测到宽度<2mm的透光线,骨水泥型和非骨水泥型植入物之间无差异。很少有论文对骨水泥型与非骨水泥型TKA进行了良好的试验。大多数研究报告在平均随访8.6年(范围5 - 18年)时生存率超过90%。
骨水泥型和非骨水泥型TKA在功能结局和生存率方面观察到相似的结果。两种手术技术均报告了高生存率,且骨水泥型TKA未提供额外益处。假设非骨水泥型假体能够实现稳定固定并缩短手术时间,作者建议在本研究的患者群体中首选非骨水泥型固定。然而,证据不足,需要进一步研究。
IV级