Teh Ooi-Kock, Hofius Daniel
Department of Plant Biology and Forest Genetics, Uppsala BioCenter, Swedish University of Agricultural Sciences (SLU) and Linnean Center of Plant Biology, SE-75007 Uppsala, Sweden.
J Exp Bot. 2014 Mar;65(5):1297-312. doi: 10.1093/jxb/ert441. Epub 2014 Jan 13.
Plants respond to pathogen attack with dynamic rearrangements of the endomembrane system and rapid redirection of membrane traffic to facilitate effective host defence. Mounting evidence indicates the involvement of endocytic, secretory, and vacuolar trafficking pathways in immune receptor activation, signal transduction, and execution of multiple defence responses including programmed cell death (PCD). Autophagy is a conserved intracellular trafficking and degradation process and has been implicated in basal immunity as well as in some forms of immune receptor-mediated vacuolar cell death. However, the regulatory interplay of autophagy and other membrane trafficking pathways in PCD and defence responses remains obscure. This review therefore highlights recent advances in the understanding of autophagic and membrane trafficking during plant immunity, and discusses emerging molecular links and functional interconnections.
植物通过内膜系统的动态重排和膜运输的快速重新定向来应对病原体攻击，以促进有效的宿主防御。越来越多的证据表明，内吞、分泌和液泡运输途径参与免疫受体激活、信号转导以及包括程序性细胞死亡（PCD）在内的多种防御反应的执行。自噬是一种保守的细胞内运输和降解过程，已被证明参与基础免疫以及某些形式的免疫受体介导的液泡细胞死亡。然而，自噬与其他膜运输途径在PCD和防御反应中的调控相互作用仍不清楚。因此，本综述重点介绍了植物免疫过程中自噬和膜运输方面的最新进展，并讨论了新出现的分子联系和功能互联。
