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切割针活检在姑息治疗环境下复发性和晚期头颈恶性肿瘤中的应用价值。

Usefulness of cutting needle biopsy in recurrent and advanced staged head and neck malignancies in a palliative setting.

作者信息

Ridder G J, Pfeiffer J

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, University Medical School Freiburg, Killianstrasse 5, 79106, Freiburg, Germany.

出版信息

Support Care Cancer. 2007 Nov;15(11):1301. doi: 10.1007/s00520-007-0237-8. Epub 2007 Mar 21.

Abstract

GOAL OF WORK

Advanced staged and recurrent head and neck malignancies require histological confirmation before planning further treatment. The purpose of this article is to focus on the clinical usefulness of cutting needle biopsies in the head and neck as a minimal invasive procedure to establish a tissue diagnosis in a palliative setting.

MATERIALS AND METHODS

A retrospective analysis on 74 core needle biopsies in 32 patients with recurrent and advanced staged head and neck malignancies was performed to determine the advantages of ultrasound-guided cutting needle biopsies compared to open biopsy and fine-needle aspiration cytology in palliative cancer treatment.

MAIN RESULTS

We experienced 100% success in obtaining high-quality histopathologic specimens. In 93.8% of the patients, a tissue core of the target organ was successfully obtained. All of the patients tolerated the procedure well without any minor or major complications.

CONCLUSIONS

Cutting needle biopsy in the head and neck is a safe and minimal-invasive procedure that can be performed in local anaesthesia on an outpatient basis. In a palliative setting, it can be recommended as an attractive alternative to both fine needle aspiration and open biopsy. It represents a simple and fast device for obtaining a tissue diagnosis with high diagnostic yield and accuracy and low morbidity.

摘要

工作目标

进展期及复发性头颈部恶性肿瘤在规划进一步治疗前需要组织学确诊。本文旨在聚焦于头颈部切割针活检作为一种微创操作在姑息治疗中用于建立组织诊断的临床实用性。

材料与方法

对32例复发性及进展期头颈部恶性肿瘤患者的74次芯针活检进行回顾性分析,以确定在姑息性癌症治疗中,超声引导下切割针活检相较于开放性活检及细针穿刺抽吸活检的优势。

主要结果

我们在获取高质量组织病理学标本方面成功率达100%。93.8%的患者成功获取了目标器官的组织芯。所有患者对该操作耐受性良好,未出现任何轻微或严重并发症。

结论

头颈部切割针活检是一种安全的微创操作,可在局部麻醉下门诊进行。在姑息治疗中,它可被推荐为细针穿刺抽吸活检和开放性活检的有吸引力的替代方法。它是一种简单快速的获取组织诊断的设备,诊断率高、准确性高且发病率低。

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