Belokhvostov A S, Lebedev S N, Sherlina S S
Radiobiologiia. 1987 Jul-Aug;27(4):505-10.
The content and fractional composition of nucleic acids of blood serum change after lethal (8 Gy) particularly superlethal (100 Gy) gamma-irradiation of rats. This concerns DNA the content of which increases by 7 times 5 h following 100 Gy irradiation. It has been shown by electrophoresis in 0.85% agarose that a heterogeneous DNA fraction with the molecular weight of (1-15) X 10(6) dalton increases. The analysis of the preparation in the polyacrylamide gel has revealed a DNA fraction that is not found in norm: the fraction possesses the electrophoretic mobility corresponding to that of nucleosome DNA.
在对大鼠进行致死剂量(8 Gy)尤其是超致死剂量(100 Gy)的γ射线照射后,血清中核酸的含量和分数组成会发生变化。这与DNA有关,在100 Gy照射后5小时,其含量增加了7倍。通过在0.85%琼脂糖中进行电泳表明,分子量为(1 - 15)×10⁶道尔顿的异质DNA组分增加。在聚丙烯酰胺凝胶中对该制剂的分析揭示了一种在正常情况下未发现的DNA组分:该组分具有与核小体DNA相对应的电泳迁移率。