Aikawa Takeshi, Shibata Mitsuhiro, Asano Moe, Hara Yasushi, Tagawa Masahiro, Orima Hiromitsu
Aikawa Veterinary Medical Center, Shinjyuku-ku, Tokyo, Japan; Nippon Veterinary and Life Science University, Kyounan-cho, Musashino-shi, Tokyo, Japan.
Vet Surg. 2014 Mar;43(3):301-7. doi: 10.1111/j.1532-950X.2014.12102.x. Epub 2014 Jan 16.
To compare data for French Bulldogs and Dachshunds that had hemilaminectomy for thoracolumbar intervertebral disc extrusion (T-L IVDE) by 1 surgeon and to evaluate the association between IVDE and congenital vertebral anomalies.
Retrospective case series.
French Bulldogs (n = 47) and 671 Dachshunds.
Age, gender, vertebral anomaly, kyphosis/kyphoscoliosis, IVDE site, non-recovery and progressive hemorrhagic myelomalacia development from grade 5 (paraplegia without deep nociception) were compared between the 2 breeds.
French Bulldogs were significantly younger (P = .00001), more likely to be male (P = .023), and more likely to have a congenital vertebral anomaly and kyphosis/kyphoscoliosis (P < .00001) than Dachshunds. The frequencies of French Bulldogs with IVDE within typical sites (T11-L3) were significantly lower (P = .0005) and within caudal sites (L3-L7) significantly higher (P = .0001) compared with Dachshunds. None of the French Bulldogs had IVDE within the kyphotic/kyphoscoliotic segment. The frequency of lumbar IVDE (L1-L5) in French Bulldogs with kyphosis/kyphoscoliosis was significantly higher (P = .003) compared with French Bulldogs without kyphosis/kyphoscoliosis. In grade 5 dogs, the risk of developing progressive hemorrhagic myelomalacia in French Bulldogs was significantly higher (P = .03) than in Dachshunds.
The distribution of IVDE site in French Bulldogs within the thoracolumbar and lumbar spine was different from Dachshunds. IVDE sites were not located at the sites of vertebral anomaly. French Bulldogs appeared to have T-L IVDE at younger ages, with higher male predisposition and higher risk of developing progressive hemorrhagic myelomalacia from grade 5 compared with Dachshunds.
比较由同一位外科医生实施胸腰椎椎间盘突出症（T-L IVDE）半椎板切除术的法国斗牛犬和腊肠犬的数据，并评估椎间盘突出症与先天性椎体异常之间的关联。
回顾性病例系列研究。
法国斗牛犬（n = 47）和671只腊肠犬。
比较两个品种在年龄、性别、椎体异常、驼背/脊柱后凸侧弯、椎间盘突出症部位、未恢复情况以及从5级（截瘫且无深部痛觉）发展为进行性出血性脊髓软化症方面的差异。
与腊肠犬相比，法国斗牛犬年龄显著更小（P = .00001），雄性比例更高（P = .023），且更易出现先天性椎体异常和驼背/脊柱后凸侧弯（P < .00001）。与腊肠犬相比，法国斗牛犬在典型部位（T11-L3）发生椎间盘突出症的频率显著更低（P = .0005），而在尾部部位（L3-L7）发生椎间盘突出症的频率显著更高（P = .0001）。没有一只法国斗牛犬在驼背/脊柱后凸侧弯节段发生椎间盘突出症。与没有驼背/脊柱后凸侧弯的法国斗牛犬相比，有驼背/脊柱后凸侧弯的法国斗牛犬腰椎椎间盘突出症（L1-L5）的发生率显著更高（P = .003）。在5级犬中，法国斗牛犬发展为进行性出血性脊髓软化症的风险显著高于腊肠犬（P = .03）。
法国斗牛犬胸腰椎和腰椎椎间盘突出症的部位分布与腊肠犬不同。椎间盘突出症部位并非位于椎体异常部位。与腊肠犬相比，法国斗牛犬似乎在更年轻的时候就发生胸腰椎椎间盘突出症，雄性易感性更高，且从5级发展为进行性出血性脊髓软化症的风险更高。
