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前列腺素和异丙肾上腺素对大鼠下颌下腺腺泡中环磷酸腺苷含量及钠钾泵活性的不同影响。

Differential effects of prostaglandins and isoproterenol on cAMP content and Na, K pump activity in rat submandibular acini.

作者信息

Martinez J R, Cassity N, Barker S

机构信息

Department of Child Health, University of Missouri School of Medicine, Columbia 65212.

出版信息

Experientia. 1987 Sep 15;43(9):1013-5. doi: 10.1007/BF01952223.

DOI:10.1007/BF01952223
PMID:2443384
Abstract

The beta-adrenergic agonist isoproterenol and prostaglandins E1 and E2 (but not F2 alpha) increased the cAMP content of rat submandibular acini in vitro, but only isoproterenol enhanced ouabain-sensitive 86Rb (K) uptake. These findings suggest that cAMP is not involved in the activation of the Na, K pump in salivary cells.

摘要

β-肾上腺素能激动剂异丙肾上腺素以及前列腺素E1和E2（而非F2α）可在体外增加大鼠下颌下腺腺泡的环磷酸腺苷（cAMP）含量，但只有异丙肾上腺素能增强哇巴因敏感的86Rb（钾）摄取。这些发现表明，cAMP不参与唾液腺细胞中钠钾泵的激活。

相似文献

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Differential effects of prostaglandins and isoproterenol on cAMP content and Na, K pump activity in rat submandibular acini.前列腺素和异丙肾上腺素对大鼠下颌下腺腺泡中环磷酸腺苷含量及钠钾泵活性的不同影响。
Experientia. 1987 Sep 15;43(9):1013-5. doi: 10.1007/BF01952223.
2
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Actions of prostaglandins E2 and F2 alpha on release of 14C-labelled mucins from rat submandibular salivary acini in vitro.前列腺素E2和F2α对体外培养的大鼠下颌下腺唾液腺泡释放14C标记粘蛋白的作用。
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引用本文的文献

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Arachidonic acid, prostaglandin E2 and leukotriene C4 levels in gingiva and submandibular salivary glands of rats fed diets containing n-3 fatty acids.喂食含n-3脂肪酸饮食的大鼠牙龈和下颌下唾液腺中花生四烯酸、前列腺素E2和白三烯C4的水平
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本文引用的文献

1
Secretory responses of the rat submandibular and parotid glands to sequential stimulation with pilocarpine and isoproterenol.大鼠颌下腺和腮腺对毛果芸香碱和异丙肾上腺素序贯刺激的分泌反应。
Arch Oral Biol. 1982;27(2):159-66. doi: 10.1016/0003-9969(82)90137-6.
2
Effects of ouabain and furosemide on saliva secretion induced by sympathomimetic agents in isolated, perfused rat submandibular glands.
Experientia. 1984 Jun 15;40(6):557-9. doi: 10.1007/BF01982328.
3
In-vivo effects of prostaglandin E1 and lysine-bradykinin on rat salivary secretions elicited by parasympathomimetic stimulation.前列腺素E1和赖氨酸缓激肽对拟副交感神经刺激诱发的大鼠唾液分泌的体内效应。
Arch Oral Biol. 1983;28(3):259-62. doi: 10.1016/0003-9969(83)90156-5.
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Regulation of tight junctional permeability in the rat parotid gland by autonomic agonists.自主激动剂对大鼠腮腺紧密连接通透性的调节
J Dent Res. 1984 Sep;63(9):1102-7. doi: 10.1177/00220345840630090101.
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Effect of transport inhibitors on secretion by perfused rat submandibular gland.
Am J Physiol. 1983 Nov;245(5 Pt 1):G711-6. doi: 10.1152/ajpgi.1983.245.5.G711.
6
A radioisotopic method for measuring the formation of adenosine 3',5'-cyclic monophosphate in incubated slices of brain.一种用于测量脑切片孵育过程中3',5'-环磷酸腺苷形成的放射性同位素方法。
J Neurochem. 1969 Dec;16(12):1609-19. doi: 10.1111/j.1471-4159.1969.tb10360.x.
7
36Cl fluxes in dispersed rat submandibular acini: effects of acetylcholine and transport inhibitors.分散的大鼠下颌下腺腺泡中的36Cl通量：乙酰胆碱和转运抑制剂的作用。
Pflugers Arch. 1985 Jan;403(1):50-4. doi: 10.1007/BF00583281.
8
42K spaces in submandibular gland of early postnatal rats: effects of carbachol and transport inhibitors.
Experientia. 1986 Sep 15;42(9):1005-6. doi: 10.1007/BF01940707.
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Identification of cellular activation mechanisms associated with salivary secretion.
Annu Rev Physiol. 1986;48:75-88. doi: 10.1146/annurev.ph.48.030186.000451.
10
Biphasic modulation of potassium release in rat parotid gland by carbachol and phenylephrine.卡巴胆碱和去氧肾上腺素对大鼠腮腺钾释放的双相调节作用。
J Pharmacol Exp Ther. 1976 Aug;198(2):375-84.