前列腺素和异丙肾上腺素对大鼠下颌下腺腺泡中环磷酸腺苷含量及钠钾泵活性的不同影响。
Differential effects of prostaglandins and isoproterenol on cAMP content and Na, K pump activity in rat submandibular acini.
作者信息
Martinez J R, Cassity N, Barker S
机构信息
Department of Child Health, University of Missouri School of Medicine, Columbia 65212.
出版信息
Experientia. 1987 Sep 15;43(9):1013-5. doi: 10.1007/BF01952223.
PMID:2443384
Abstract
The beta-adrenergic agonist isoproterenol and prostaglandins E1 and E2 (but not F2 alpha) increased the cAMP content of rat submandibular acini in vitro, but only isoproterenol enhanced ouabain-sensitive 86Rb (K) uptake. These findings suggest that cAMP is not involved in the activation of the Na, K pump in salivary cells.
摘要
β-肾上腺素能激动剂异丙肾上腺素以及前列腺素E1和E2（而非F2α）可在体外增加大鼠下颌下腺腺泡的环磷酸腺苷（cAMP）含量，但只有异丙肾上腺素能增强哇巴因敏感的86Rb（钾）摄取。这些发现表明，cAMP不参与唾液腺细胞中钠钾泵的激活。
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