Justino Celine I L, Duarte Armando C, Rocha-Santos Teresa A P
Department of Chemistry & CESAM, University of Aveiro, Campus de Santiago, 3810-193 Aveiro, Portugal.
ISEIT/Viseu, Instituto Piaget, Estrada do Alto do Gaio, Galifonge, 3515-776 Lordosa, Viseu, Portugal.
Trends Analyt Chem. 2016 Dec;85:36-60. doi: 10.1016/j.trac.2016.04.004. Epub 2016 Apr 8.
Sensors and biosensors have been increasingly used for clinical analysis due to their miniaturization and portability, allowing the construction of diagnostic devices for point-of-care testing. This paper presents an up-to-date overview and comparison of the analytical performance of sensors and biosensors recently used in clinical analysis. This includes cancer and cardiac biomarkers, hormones, biomolecules, neurotransmitters, bacteria, virus and cancer cells, along with related significant advances since 2011. Some methods of enhancing the analytical performance of sensors and biosensors through their figures of merit are also discussed.
由于传感器和生物传感器的小型化和便携性，它们在临床分析中的应用越来越广泛，这使得即时检测诊断设备的构建成为可能。本文对近期用于临床分析的传感器和生物传感器的分析性能进行了最新综述和比较。这包括癌症和心脏生物标志物、激素、生物分子、神经递质、细菌、病毒和癌细胞，以及自2011年以来的相关重大进展。还讨论了一些通过传感器和生物传感器的品质因数来提高其分析性能的方法。
