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营养治疗、磷酸盐控制与肾脏保护。

Nutritional therapy, phosphate control and renal protection.

机构信息

Division of Nephrology and Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden.

出版信息

Nephron Clin Pract. 2014;126(1):1-7. doi: 10.1159/000357679. Epub 2014 Jan 11.

Abstract

Dietary management of chronic kidney disease (CKD) focusses on limiting the intake of substances that might accumulate to toxic levels (such as potassium, phosphorus or salt) and, although still a matter of debate for some, restricting dietary protein to retard kidney damage. Recent evidence brings the opportunity to revisit the role of a healthy diet on disease progression and on some of the cardiometabolic complications of moderate/advanced CKD, such as inflammation or oxidative stress control. This review provides a brief overview of dietary strategies that delay CKD progression and CKD complications, and discusses currently limited data addressing the development of malnutrition and protein-energy wasting before dialysis initiation.

摘要

慢性肾脏病(CKD)的饮食管理侧重于限制摄入可能积聚到毒性水平的物质(如钾、磷或盐),并且尽管对于某些人来说仍然存在争议,但限制饮食蛋白质以延缓肾脏损伤。最近的证据为重新审视健康饮食在疾病进展和 CKD 中一些代谢并发症(如炎症或氧化应激控制)中的作用提供了机会。本文简要概述了延缓 CKD 进展和 CKD 并发症的饮食策略,并讨论了目前关于透析前营养不良和蛋白质能量消耗发展的有限数据。

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