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How useful are blood and stool biomarkers for detecting subclinical mucosal inflammation in ulcerative colitis?

作者信息

Ye Byong Duk

机构信息

Department of Gastroenterology and Inflammatory Bowel Disease Center, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 138-736, Republic of Korea,

出版信息

Dig Dis Sci. 2014 Apr;59(4):706-7. doi: 10.1007/s10620-013-2985-2. Epub 2014 Jan 17.

DOI:10.1007/s10620-013-2985-2
PMID:24435183
Abstract
摘要

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How useful are blood and stool biomarkers for detecting subclinical mucosal inflammation in ulcerative colitis?血液和粪便生物标志物在检测溃疡性结肠炎亚临床黏膜炎症方面有多大用处?
Dig Dis Sci. 2014 Apr;59(4):706-7. doi: 10.1007/s10620-013-2985-2. Epub 2014 Jan 17.
2
Correlations of C-reactive protein levels and erythrocyte sedimentation rates with endoscopic activity indices in patients with ulcerative colitis.溃疡性结肠炎患者 C 反应蛋白水平和红细胞沉降率与内镜活动指数的相关性。
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[Ulcerative colitis. Clinical diagnosis].[溃疡性结肠炎。临床诊断]
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本文引用的文献

1
Correlations of C-reactive protein levels and erythrocyte sedimentation rates with endoscopic activity indices in patients with ulcerative colitis.溃疡性结肠炎患者 C 反应蛋白水平和红细胞沉降率与内镜活动指数的相关性。
Dig Dis Sci. 2014 Apr;59(4):829-37. doi: 10.1007/s10620-013-2907-3. Epub 2013 Dec 19.
2
Reliability and initial validation of the ulcerative colitis endoscopic index of severity.溃疡性结肠炎内镜严重指数的可靠性和初步验证。
Gastroenterology. 2013 Nov;145(5):987-95. doi: 10.1053/j.gastro.2013.07.024. Epub 2013 Jul 25.
3
Fecal calprotectin more accurately reflects endoscopic activity of ulcerative colitis than the Lichtiger Index, C-reactive protein, platelets, hemoglobin, and blood leukocytes.
粪便钙卫蛋白比 Lichtiger 指数、C 反应蛋白、血小板、血红蛋白和血白细胞更能准确反映溃疡性结肠炎的内镜活动。
Inflamm Bowel Dis. 2013 Feb;19(2):332-41. doi: 10.1097/MIB.0b013e3182810066.
4
Validation of the ulcerative colitis colonoscopic index of severity and its correlation with disease activity measures.溃疡性结肠炎内镜严重程度指数的验证及其与疾病活动度指标的相关性。
Clin Gastroenterol Hepatol. 2013 Jan;11(1):49-54.e1. doi: 10.1016/j.cgh.2012.08.003. Epub 2012 Aug 16.
5
Evaluation of disease activity in IBD at the time of diagnosis by the use of clinical, biochemical, and fecal markers.在诊断时通过临床、生化和粪便标志物评估炎症性肠病的疾病活动度。
Scand J Gastroenterol. 2011 Sep;46(9):1081-91. doi: 10.3109/00365521.2011.584897. Epub 2011 May 30.
6
Correlation of C-reactive protein with clinical and endoscopic activity in patients with ulcerative colitis.C-反应蛋白与溃疡性结肠炎患者临床和内镜活动的相关性。
Dig Dis Sci. 2011 Jun;56(6):1801-5. doi: 10.1007/s10620-010-1496-7. Epub 2010 Dec 3.
7
Ulcerative colitis: correlation of the Rachmilewitz endoscopic activity index with fecal calprotectin, clinical activity, C-reactive protein, and blood leukocytes.溃疡性结肠炎:Rachmilewitz 内镜活动指数与粪便钙卫蛋白、临床活动、C 反应蛋白和血白细胞的相关性。
Inflamm Bowel Dis. 2009 Dec;15(12):1851-8. doi: 10.1002/ibd.20986. Epub 2009 May 21.
8
Correlations among total colonoscopic findings, clinical symptoms, and laboratory markers in ulcerative colitis.溃疡性结肠炎中全结肠镜检查结果、临床症状及实验室指标之间的相关性
J Gastroenterol Hepatol. 2008 Dec;23 Suppl 2:S262-7. doi: 10.1111/j.1440-1746.2008.05413.x.
9
Noninvasive markers in the assessment of intestinal inflammation in inflammatory bowel diseases: performance of fecal lactoferrin, calprotectin, and PMN-elastase, CRP, and clinical indices.炎症性肠病中肠道炎症评估的非侵入性标志物:粪便乳铁蛋白、钙卫蛋白、PMN弹性蛋白酶、CRP及临床指标的表现
Am J Gastroenterol. 2008 Jan;103(1):162-9. doi: 10.1111/j.1572-0241.2007.01556.x. Epub 2007 Oct 4.
10
Cortisone in ulcerative colitis; final report on a therapeutic trial.可的松治疗溃疡性结肠炎;一项治疗试验的最终报告
Br Med J. 1955 Oct 29;2(4947):1041-8. doi: 10.1136/bmj.2.4947.1041.