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鼻中隔成形术后鼻腔填塞:心肺影响。

Nasal packing after septoplasty: cardiopulmonary impact.

机构信息

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, McMaster University, Hamilton, Ontario, Canada.

Department of Anesthesiology, University of Toronto, Toronto, Ontario, Canada.

出版信息

JAMA Otolaryngol Head Neck Surg. 2014 Mar;140(3):253-8. doi: 10.1001/jamaoto.2013.6335.

Abstract

IMPORTANCE

Bilateral anterior nasal packing is used after septoplasty with the goals of decreasing the risk of postoperative bleeding and adhesions. However, multiple studies caution against the use of nasal packing because of the risk of cardiopulmonary complications.

OBJECTIVE

To evaluate the cardiopulmonary risks associated with bilateral anterior nasal packing after septoplasty.

EVIDENCE REVIEW

A literature review was conducted by 2 independent reviewers using EMBASE, Ovid, Medline, PubMed, Google Scholar, Cochrane Central Register of Controlled Trials (CENTRAL), and reference list review from January 1966 to September 2012 to identify studies assessing nasal packing after septoplasty. The studies were reviewed and assigned an Oxford level of evidence grade, Detsky score, and Methodological Index for Nonrandomized Studies (MINORS) score. Data were extracted for arterial blood gases, oxygen desaturations, oxygen saturations, and adverse outcomes. Pooled estimates for randomized studies were performed when possible.

FINDINGS

Fourteen studies conducted between 1973 and 2011 were included: 2 randomized clinical trials (RCTs) with a total of 119 patients and 12 prospective observational studies with a total of 356 patients. Nine studies showed a significant change within 1 of the cardiopulmonary parameters investigated. However, there was no consistency in changes across both observational and randomized studies. Furthermore, pooled estimates for cardiopulmonary parameters were all nonsignificant: standard mean differences of the pooled results of the RCTs were 0.05 (95% CI, -0.31 to 0.41) for arterial pH, 0.08 (95% CI, -0.30 to 0.46) for Paco2, and -0.32 (95% CI, -1.28 to 0.63) for Pao2. There were no major cardiopulmonary complications after nasal packing.

CONCLUSIONS AND RELEVANCE

Bilateral anterior nasal packing does not seem to cause adverse cardiopulmonary changes after septoplasty.

摘要

重要性

鼻中隔成形术后使用双侧前鼻腔填塞的目的是降低术后出血和粘连的风险。然而,多项研究警告不要使用鼻腔填塞,因为存在心肺并发症的风险。

目的

评估鼻中隔成形术后双侧前鼻腔填塞与心肺相关的风险。

证据回顾

两位独立评审员通过 EMBASE、Ovid、Medline、PubMed、Google Scholar、Cochrane 对照试验中心注册(CENTRAL)和 1966 年 1 月至 2012 年 9 月的参考文献回顾进行文献综述,以确定评估鼻中隔成形术后鼻腔填塞的研究。对研究进行了审查并分配了牛津证据等级、Detsky 评分和非随机研究方法学指数(MINORS)评分。提取了动脉血气、氧饱和度和不良结局的数据。当可能时,对随机研究进行了汇总估计。

发现

共纳入了 1973 年至 2011 年期间进行的 14 项研究:2 项随机临床试验(RCT)共 119 例患者和 12 项前瞻性观察性研究共 356 例患者。9 项研究显示,在调查的心肺参数中,有 1 项发生了显著变化。然而,观察性研究和随机研究之间并没有一致性的变化。此外,心肺参数的汇总估计均无统计学意义:RCT 汇总结果的标准均数差为动脉 pH 值为 0.05(95%CI,-0.31 至 0.41),Paco2 为 0.08(95%CI,-0.30 至 0.46),Pao2 为-0.32(95%CI,-1.28 至 0.63)。鼻腔填塞后无重大心肺并发症。

结论和相关性

双侧前鼻腔填塞似乎不会导致鼻中隔成形术后出现不良的心肺变化。

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