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[抑郁症对女性急性心血管疾病风险的影响]

[The influence of depression on the risk of acute cardiovascular diseases in women].

作者信息

Gafarov V V, Panov D O, Gromova E A, Gagulin I V, Gafarova A V

出版信息

Klin Med (Mosk). 2013;91(9):25-9.

PMID:24437151
Abstract

The aim of the work was to elucidate the relation of depression to the awareness of and attitude to health as well as effect of depression on the risk of acute cardiovascular diseases in women aged 25-64 yr during 16 years. A random representative sample of 870 women residing in Novosibirsk was examined in the framework of MONICA-psychosocial program (WHO) in 1994. The MOPSY test was used for the purpose. All new cases of myocardial infarction and stroke were recorded. The prevalence of depression was estimated at 55.2%. Positive self-evaluation of health decreased as severity of depression increased. Almost 100% of the patients with this condition complained of poor health and were dissatisfied with the care given to improve it. Severe depression is associated with stress experienced at the workplace and in the family; such women rarely keep to the diet and make physical exercises. The relative risk of myocardial infarction and stroke in depressed women during 16 years was 2.53 (p < 0.05) and 4.63 (p < 0.05) higher respectively than in the absence of depression.

摘要

这项研究的目的是阐明抑郁症与健康意识和态度之间的关系,以及抑郁症对16年间25至64岁女性患急性心血管疾病风险的影响。1994年,在世界卫生组织(WHO)的莫妮卡-心理社会项目框架下,对居住在新西伯利亚的870名女性进行了随机抽样调查。为此使用了MOPSY测试。记录了所有心肌梗死和中风的新病例。抑郁症的患病率估计为55.2%。随着抑郁症严重程度的增加,对健康的积极自我评价降低。几乎100%患有这种疾病的患者抱怨健康状况不佳,并对为改善健康所提供的护理不满意。严重抑郁症与在工作场所和家庭中经历的压力有关;这类女性很少坚持饮食和进行体育锻炼。在16年间,抑郁症女性患心肌梗死和中风的相对风险分别比无抑郁症女性高2.53(p<0.05)和4.63(p<0.05)。

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