Lertanekawattana Sujet, Anantapreecha Surapee, Jiraphongsa Chuleeporn, Duan-ngern Pawinee, Potjalongsin Sathit, Wiittayabamrung Wisanu, Daroon Pamol, Techolarn Meta
Nong Khai Hospital, Ministry of Public Health, Nong Khai.
Department of Medical Science, Ministry of Public Health, Nonthaburi.
Southeast Asian J Trop Med Public Health. 2013 Sep;44(5):780-90.
We conducted a cross sectional study at three hospitals of Nong Khai Province, Thailand to determine the prevalence and characteristics of dengue and chikungunya infection among patients who sought care. The study population was acute febrile patients who visited these hospitals during 1 August -31 October, 2010 who were aged 2-60 years and had clinical symptoms compatible with the case definition. Dengue and chikungunya cases were confirmed by an ELISA IgM titer or RT-PCR. We also reviewed surveillance data of dengue and chikungunya infections from 2003-2009. Of the 200 participants recruited into the study, 103 patients (51.5%) were confirmed to have acute dengue infection; dengue serotype 2 was the most prevalence serotype. The ages of confirmed dengue cases ranged from 2-37 years old. The distribution of cases showed that dengue morbidity tended to be clustered in adjacent areas, particularly in Mueang District. Only a small proportion of the patients uses mosquito repellant and had screens on their windows. One patient (0.5%) had laboratory confirmed chikungunya infection. She was from Rattanawapi District, an area where no chikungunya had been reported before. Since the disease varies by age and geographic location, increased awareness of health care workers and public health officers about the diseases in the area is needed for early detection of cases and to promote early prevention and control measures.
我们在泰国廊开府的三家医院开展了一项横断面研究，以确定在寻求治疗的患者中登革热和基孔肯雅热感染的患病率及特征。研究对象为2010年8月1日至10月31日期间前往这些医院就诊的2至60岁急性发热患者，且其临床症状符合病例定义。登革热和基孔肯雅热病例通过ELISA IgM滴度或RT-PCR确诊。我们还回顾了2003 - 2009年登革热和基孔肯雅热感染的监测数据。在纳入研究的200名参与者中，103例患者（51.5%）被确诊为急性登革热感染；登革热2型是最常见的血清型。确诊登革热病例的年龄范围为2至37岁。病例分布显示，登革热发病倾向于在相邻地区聚集，尤其是在直辖县。只有一小部分患者使用驱蚊剂且窗户有纱窗。一名患者（0.5%）经实验室确诊为基孔肯雅热感染。她来自拉塔纳瓦皮县，该地区此前未报告过基孔肯雅热病例。由于该病因年龄和地理位置而异，需要提高医护人员和公共卫生官员对该地区疾病的认识，以便早期发现病例并促进早期预防和控制措施。
