美国维尔京群岛基于人群的 1 型糖尿病队列的全因死亡率。

All-cause mortality in a population-based type 1 diabetes cohort in the U.S. Virgin Islands.

机构信息

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, United States.

出版信息

Diabetes Res Clin Pract. 2014 Mar;103(3):504-9. doi: 10.1016/j.diabres.2013.12.014. Epub 2013 Dec 27.

DOI:10.1016/j.diabres.2013.12.014

PMID:24439208

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4516118/

Abstract

OBJECTIVE

Type 1 diabetes remains a significant source of premature mortality; however, its burden has not been assessed in the U.S. Virgin Islands (USVI). As such, the objective of this study was to estimate type 1 diabetes mortality in a population-based registry sample in the USVI.

RESEARCH DESIGN AND METHODS

We report overall and 20-year mortality in the USVI Childhood (<19 years old) Diabetes Registry Cohort diagnosed 1979-2005. Recent data for non-Hispanic blacks from the Allegheny County, PA population-based type 1 diabetes registry were used to compare mortality in the USVI to the contiguous U.S.

RESULTS

As of December 31, 2010, the vital status of 94 of 103 total cases was confirmed (91.3%) with mean diabetes duration 16.8 ± 7.0 years. No deaths were observed in the 2000-2005 cohort. The overall mortality rates for those diagnosed 1979-1989 and 1990-1999 were 1852 and 782 per 100,000 person-years, respectively. Overall cumulative survival for USVI was 98% (95% CI: 97-99) at 10 years, 92% (95% CI: 89-95) at 15 years and 73% (95% CI: 66-80) at 20 years. The overall SMR for non-Hispanic blacks in the USVI was 5.8 (95% CI: 2.7-8.8). Overall mortality and cumulative survival for non-Hispanic blacks did not differ between the USVI and Allegheny County, PA.

CONCLUSIONS

This study, as the first type 1 diabetes mortality follow-up in the USVI, confirmed previous findings of poor disease outcomes in racial/ethnic minorities with type 1 diabetes.

摘要

目的

1 型糖尿病仍然是导致过早死亡的一个重要原因；然而，在美国维尔京群岛（USVI）尚未对其负担进行评估。因此，本研究的目的是评估 USVI 人群基于注册的 1 型糖尿病死亡病例。

研究设计和方法

我们报告了 USVI 儿童（<19 岁）糖尿病注册队列中 1979-2005 年间诊断的病例的总体和 20 年死亡率。使用宾夕法尼亚州阿勒格尼县人群中 1 型糖尿病注册的非西班牙裔黑人的最新数据，将 USVI 的死亡率与美国本土进行比较。

结果

截至 2010 年 12 月 31 日，103 例总病例中有 94 例（91.3%）的生命状态得到了确认，平均糖尿病病程为 16.8 ± 7.0 年。2000-2005 年队列中未观察到死亡病例。1979-1989 年和 1990-1999 年诊断的病例的总死亡率分别为 1852 和 782 例/100000 人年。USVI 的整体累积生存率为 10 年时 98%（95%CI：97-99），15 年时 92%（95%CI：89-95），20 年时 73%（95%CI：66-80）。USVI 非西班牙裔黑人的总体 SMR 为 5.8（95%CI：2.7-8.8）。非西班牙裔黑人的总死亡率和累积生存率在 USVI 和宾夕法尼亚州阿勒格尼县之间没有差异。