Tull E S, Roseman J M, Christian C L
Diabetes Research Center, School of Public Health, University of Pittsburgh, Pennsylvania.
Diabetes Care. 1991 Jul;14(7):558-64. doi: 10.2337/diacare.14.7.558.
The epidemiology of insulin-dependent diabetes mellitus (IDDM) was evaluated in a predominantly black population in the U.S. Virgin Islands.
Primary ascertainment of diabetic subjects was by retrospective review of hospital and clinic records, and IDDM was defined by Diabetes Epidemiology Research International Group criteria.
For the period 1979-1988, 28 children less than 15 yr of age were diagnosed with IDDM resulting in an average annual IDDM incidence rate (IR) of 7.5/100,000 (95% confidence interval 4.7-10.3). A significant increase in IDDM incidence (P less than 0.01) was observed when the IR rose to 28.4/100,000 in 1984. White children had the highest IR (28.9/100,000). The IR for Hispanics (7.2/100,000) was slightly higher than that for blacks (5.9/100,000). Among black children, a slight but nonsignificant male excess in incidence was observed (male-female ratio 1.5). When black or Hispanic patients were compared with age-matched control subjects with respect to grandparental race, the diabetic subjects had a greater percentage of white ancestry (P less than 0.02 and P less than 0.05, respectively). The incidence of IDDM in Caribbean blacks (West Indians) in the U.S. Virgin Islands was similar to blacks in the U.S.
The epidemic of IDDM in 1984 provides support for a possible pandemic in the early 1980s.
对美属维尔京群岛以黑人为主的人群中胰岛素依赖型糖尿病（IDDM）的流行病学情况进行评估。
通过回顾医院和诊所记录对糖尿病患者进行初步确诊，IDDM依据国际糖尿病流行病学研究组的标准来定义。
在1979年至1988年期间，28名15岁以下儿童被诊断为IDDM，年均IDDM发病率（IR）为7.5/100,000（95%置信区间4.7 - 10.3）。1984年IR升至28.4/100,000时，观察到IDDM发病率显著上升（P < 0.01）。白人儿童的IR最高（28.9/100,000）。西班牙裔的IR（7.2/100,000）略高于黑人（5.9/100,000）。在黑人儿童中，发病率存在轻微但不显著的男性偏高现象（男女比例为1.5）。当将黑人或西班牙裔患者与年龄匹配的对照受试者就祖父母种族进行比较时，糖尿病受试者的白人血统比例更高（分别为P < 0.02和P < 0.05）。美属维尔京群岛加勒比黑人（西印度人）中的IDDM发病率与美国黑人相似。
1984年IDDM的流行情况为20世纪80年代初可能存在的大流行提供了支持。
