Peng Xiaorong, Wu Haibo, Jin Changzhong, Yao Hangping, Lu Xiangyun, Cheng Linfang, Wu Nanping
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, School of Medicine, Zhejiang University, 79 Qingchun Road, Hangzhou, 310003, Zhejiang, China,
Virus Genes. 2014 Apr;48(2):391-6. doi: 10.1007/s11262-014-1033-4. Epub 2014 Jan 18.
Two H2N7 avian influenza viruses (AIVs) were isolated from domestic ducks in live poultry markets in Zhejiang Province, Eastern China, 2013. All viruses were characterized by whole-genome sequencing with subsequent phylogenetic analysis and genetic comparison. Phylogenetic analysis of all eight viral genes showed that the viruses clustered in the Eurasian lineage of AIVs and originated from genes reassortment among different viruses co-circulating in domestic ducks in Eastern China. The hemagglutinin cleavage site of all viruses indicated that the two strains were low-pathogenic avian influenza viruses. Considering the important role of the domestic ducks in the dissemination and reassortment of AIVs, continued surveillance of circulating H2 subtype AIVs in domestic ducks in live poultry markets is needed.
2013年，在中国东部浙江省的活禽市场中，从家鸭体内分离出两株H2N7禽流感病毒（AIV）。所有病毒均通过全基因组测序及随后的系统发育分析和基因比较进行特征鉴定。对所有八个病毒基因的系统发育分析表明，这些病毒聚集在AIV的欧亚谱系中，并且起源于中国东部家鸭体内共同传播的不同病毒之间的基因重配。所有病毒的血凝素裂解位点表明这两株病毒为低致病性禽流感病毒。鉴于家鸭在AIV传播和重配中的重要作用，需要持续监测活禽市场家鸭体内H2亚型AIV的流行情况。
