von Herbay A, Windler F, Heckmayr M, Langkowski J, Kraas E, Otto H F
Pathologisches Institut der Universität Heidelberg.
Dtsch Med Wochenschr. 1987 Oct 16;112(42):1621-5. doi: 10.1055/s-2008-1068303.
A large nonresectable upper-abdominal tumor in a 61-year-old woman was found to have been caused by inflammatory infiltration and mechanical obstruction of the mesenteric lymph nodes resulting in obstruction to lymphatic flow. Biopsy at the root of the mesentery and of abdominal lymph nodes raised the suspicion of Whipple's disease, a diagnosis confirmed by a small-intestine biopsy. Long-term antibiotic treatment was successful. Quantitative changes in the composition of the T-cell subpopulations at the time of the diagnosis reverted to normal in the course of treatment.
一名61岁女性患有不可切除的上腹部大肿瘤，经检查发现是由肠系膜淋巴结的炎症浸润和机械性梗阻导致淋巴液流动受阻所致。肠系膜根部和腹部淋巴结活检引发了惠普尔病的怀疑，小肠活检确诊了该病。长期抗生素治疗取得成功。诊断时T细胞亚群组成的定量变化在治疗过程中恢复正常。
