Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran, Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Science Institute, Tehran University of Medical Sciences, Tehran, Iran, Development of Research and Technology Center, Deputy of Research and Technology, Ministry of Health and Medical Education, Tehran, Iran.
Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Science Institute, Tehran University of Medical Sciences, Tehran, Iran Digestive Disease Research Institute, Shariati Hospital, Tehran University of Medical Sciences.
Arch Iran Med. 2014 Jan;17(1):54-61.
Non-communicable diseases (NCDs) and their risk factors are the major public health problems. There are some documented trend and point estimations of metabolic risk factors for Iranian population but there are little information about their exposure distribution at sub-national level and no information about their trends and their effects on the population health.
The present study protocol is aimed to provide the standard structure definitions, organization, data sources, methods of data gathering or generating, and data on trend analysis of the metabolic risk factors in NASBOD study. We will estimate 1990 to 2013 trends of prevalence, years of life lost due to premature mortality (YLLs), and years lived with disability (YLDs) and disability-adjusted life years DALYs for MRFs by gender, age group, and province. We will also quantify the uncertainty interval for the estimates of interest.
The findings of study could provide practical information regarding metabolic risk factors and their burden for better health policy to reduce the burden of diseases, and to plan cost-effective preventive strategies. The results also could be used for future complementary global, regional, national, and sub national studies.
非传染性疾病（NCDs）及其风险因素是主要的公共卫生问题。有一些关于伊朗人口代谢风险因素的已有趋势和点估计的记录，但关于它们在国家以下一级的暴露分布的信息很少，也没有关于它们的趋势及其对人口健康的影响的信息。
本研究方案旨在为 NASBOD 研究中的代谢风险因素的标准结构定义、组织、数据来源、数据收集或生成方法以及趋势分析提供数据。我们将按性别、年龄组和省份估计 1990 年至 2013 年流行率、因过早死亡导致的生命损失年（YLLs）和残疾生活年（YLDs）以及残疾调整生命年（DALYs）的趋势。我们还将量化有关估计的不确定性区间。
该研究的结果可以提供有关代谢风险因素及其负担的实用信息，以便制定更好的卫生政策，减轻疾病负担，并规划具有成本效益的预防策略。研究结果还可用于未来的全球、区域、国家和国家以下各级的补充研究。
