Gać Paweł, Sobieszczańska Małgorzata
Department of Pathophysiology, Wroclaw Medical University, Marcinkowskiego 1, PL 50-368 Wrocław, Poland.
Department of Pathophysiology, Wroclaw Medical University, Marcinkowskiego 1, PL 50-368 Wrocław, Poland.
Environ Toxicol Pharmacol. 2014 Jan;37(1):404-13. doi: 10.1016/j.etap.2013.12.014. Epub 2014 Jan 2.
This report was intended to evaluate the effect of cigarette smoke on heart rate variability (HRV) in patients with arterial hypertension (AH). 223 individuals were qalified to the studies. The following groups of patients not suffering from other disease which may affect HRV were delineated: 1 - patients with AH (n=145); 2 - patients without AH (n=48). In group 1 the following patient groups were studied: A - active smokers (n=42), B - non-smokers exposed to cigarette smoke (n=30), C - non-smokers not exposed to tobacco smoke (n=34), D - former smokers (n=26). A time domain HRV analysis was carried out. Group 1 versus group 2 manifested significantly lower mean values of most parameters in the HRV time domain analysis. Subgroups A, B and D versus subgroup C also exhibited significantly lower mean values of most parameters in the HRV time domain analysis. Active cigarette smoking and passive exposure to tobacco smoke represented independent risk factors for a decreased HRV.
Active and passive exposure to cigarette smoke decreases HRV in hypertensive patients.
本报告旨在评估香烟烟雾对动脉高血压（AH）患者心率变异性（HRV）的影响。223名个体符合研究条件。划定了以下未患可能影响HRV的其他疾病的患者组：1 - AH患者（n = 145）；2 - 无AH患者（n = 48）。在第1组中，研究了以下患者亚组：A - 现吸烟者（n = 42），B - 接触香烟烟雾的非吸烟者（n = 30），C - 未接触烟草烟雾的非吸烟者（n = 34），D - 既往吸烟者（n = 26）。进行了时域HRV分析。在HRV时域分析中，第1组与第2组相比，大多数参数的平均值显著更低。亚组A、B和D与亚组C相比，在HRV时域分析中大多数参数的平均值也显著更低。主动吸烟和被动接触烟草烟雾是HRV降低的独立危险因素。
主动和被动接触香烟烟雾会降低高血压患者的HRV。
