Nomura Kazuhiro, Oshima Takeshi, Maki Atsuko, Suzuki Takahiro, Higashi Kenjiro, Watanabe Mika, Kobayashi Toshimitsu
Department of Otolaryngology-Head and Neck Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-cho, Aoba-ku, Sendai, Miyagi 980-8574, Japan.
Ear Nose Throat J. 2014 Jan;93(1):E29-31.
Chondro-osseous respiratory epithelial adenomatoid hamartoma (COREAH) is an extremely rare type of hamartoma. To the best of our knowledge, only 1 case has been previously reported. A 7-year-old girl presented with a case of COREAH of the bilateral nasal cavities. Polypous masses in both nasal cavities were resected endoscopically, and they were histologically diagnosed as COREAH. A large polypous mass recurred 1 year postsurgically on the right side only. A second endoscopic surgery was performed, and the lesion was confirmed to be recurrent COREAH. Hamartoma of the nasal cavity is rare and is generally considered to be self-limiting. This case suggests that nasal hamartomas may have neoplastic characteristics, and therefore require complete resection.
软骨-骨化性呼吸上皮腺样错构瘤(COREAH)是一种极其罕见的错构构错构瘤。据我们所知,此前仅报道过1例。一名7岁女孩被诊断为双侧鼻腔COREAH。通过鼻内镜切除了双侧鼻腔的息肉样肿物,组织学诊断为COREAH。术后1年,仅右侧出现一个大的息肉样肿物复发。进行了第二次鼻内镜手术,证实病变为复发性COREAH。鼻腔错构瘤罕见,通常被认为是自限性的。该病例提示鼻腔错构瘤可能具有肿瘤特征,因此需要完整切除。